Skip to Content
Merck
All Photos(2)

Key Documents

View All Documentation

189782

Sigma-Aldrich

4-Oxo-4H-1-benzopyran-2-carboxylic acid

97%

Synonym(s):

4-Oxo-4H-1-Benzopyran-2-carboxylic acid, Chromocarb, Chromone-2-carboxylic acid

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Empirical Formula (Hill Notation):
C10H6O4
CAS Number:
4940-39-0
Molecular Weight:
190.15
EC Number:
225-583-0
MDL number:
MFCD00006838
UNSPSC Code:
12352100
PubChem Substance ID:
24851396
NACRES:
NA.22

Assay

97%

form

powder

mp

260 °C (dec.) (lit.)

solubility

alcohol: soluble
ammonium hydroxide: soluble
water: very slightly soluble

functional group

carboxylic acid
ketone

SMILES string

OC(=O)C1=CC(=O)c2ccccc2O1

InChI

1S/C10H6O4/c11-7-5-9(10(12)13)14-8-4-2-1-3-6(7)8/h1-5H,(H,12,13)

InChI key

RVMGXWBCQGAWBR-UHFFFAOYSA-N

Gene Information

human ... PTPN1(5770)

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

Nasal absorption of 4-oxo-4H-1-benzopyran-2-carboxylic acid has been investigated in the male Wistar rat.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BGBC3679V
MKBQ4440V
MKBJ5749V
MKBF6220V
02619JD

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Stefano Alcaro et al.
Bioorganic & medicinal chemistry letters, 20(9), 2709-2712 (2010-04-13)
Chromone carboxylic acids were evaluated as human monoamine oxidase A and B (hMAO-A and hMAO-B) inhibitors. The biological data indicated that only chromone-3-carboxylic acid is a potent hMAO-B inhibitor, with a high degree of selectivity for hMAO-B compared to hMAO-A.
Chromone-2-carboxylic acids: roles of acidity and lipophilicity in drug disposition.
D A Smith et al.
Drug metabolism reviews, 16(4), 365-388 (1985-01-01)
A N Fisher et al.
The Journal of pharmacy and pharmacology, 39(5), 357-362 (1987-05-01)
The nasal absorption of a range of water-soluble compounds with different molecular weights, 4-oxo-4H-1-benzopyran-2-carboxylic acid (mol. wt 190), p-aminohippuric acid (mol. wt 194), inulin (mol. wt 5200) and dextran (mol. wt 70,000), has been investigated in the male Wistar rat.
J Swarbrick et al.
Journal of pharmaceutical sciences, 73(10), 1352-1355 (1984-10-01)
The aim of this study was to establish whether ionized as well as un-ionized forms of certain 4-oxo-4H-1-benzopyran-2-carboxylic acids (chromone-2-carboxylic acids) with pKa values less than 2 permeated through excised human skin and, if so, to determine the permeability coefficients

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service