SML1379

Seratrodast

≥98% (HPLC)

• Synonym(s): (±)-7-(3,5,6-Trimethyl-1,4-benzoquinon-2-yl)-7-phenylheptanoic acid, AA-2414
• Empirical Formula (Hill Notation): C₂₂H₂₆O₄
• CAS Number: 112665-43-7
• Molecular Weight: 354.44
• MDL number: MFCD00875701
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825828

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 25 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: O=C(C(C)=C1C)C(C)=C(C(CCCCCC(O)=O)C2=CC=CC=C2)C1=O
• InChI: 1S/C22H26O4/c1-14-15(2)22(26)20(16(3)21(14)25)18(17-10-6-4-7-11-17)12-8-5-9-13-19(23)24/h4,6-7,10-11,18H,5,8-9,12-13H2,1-3H3,(H,23,24)
• InChI key: ZBVKEHDGYSLCCC-UHFFFAOYSA-N
• Gene Information: human ... TBXA2R(6915)

Description

Biochem/physiol Actions

Seratrodast is a thromboxane A2 (TXA2) receptor (TP receptor) antagonist with anti-asthmatic activity. Seratrodast inhibits the bronchconstriction induced by leukotriene D4 (LTD4), and platelet activating factor (PAF) with a long duration of action.

Safety Information

• Pictograms: GHS08
• Signal Word: Warning
• Hazard Statements: H361
• Precautionary Statements: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable