SAB5702166

[KO Validated]Anti-ATG7 Antibody, clone 3X1W4, Rabbit Monoclonal

• Synonym(s): ATG7,APG7-LIKE,APG7L,GSA7,Apg7/Atg7
• UNSPSC Code: 12352203
• NACRES: NA.46

Properties

• biological source: rabbit
• Quality Level: 100
• material: colorless
• clone: 3X1W4, monoclonal
• form: liquid
• mol wt: 77 kDa
• species reactivity: rat, human, rat
• concentration: 1 mg/mL
• technique(s): immunohistochemistry: 1:50 - 1:200; immunoprecipitation (IP): 1:50 - 1:200; western blot: 1:500 - 1:2000
• color: colorless
• isotype: IgG
• immunogen sequence: MAAATGDPGLSKLQFAPFSSALDVGFWHELTQKKLNEYRLDEAPKDIKGYYYNGDSAGLPARLTLEFSAFDMSAPTPARCCPAIGTLYNTNTLESFKTAD
• UniProt accession no.: O95352
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... ATG7(10533)

Description

General description

This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Atg7(Apg7) (O95352).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB, IHC, IP

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1