SAB4500900

Anti-LMTK2 antibody produced in rabbit

affinity isolated antibody

• Synonym(s): Apoptosis-associated tyrosine kinase 2, Brain-enriched kinase, Kinase/phosphatase/inhibitor 2, Lemur tyrosine kinase 2, Serine/threonine protein kinase KPI-2
• MDL number: MFCD06798864
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 164 kDa
• species reactivity: human
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:20000; immunofluorescence: 1:100-1:500; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI accession no.: Q8IWU2
• UniProt accession no.: Q8IWU2
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... LMTK2(22853)

Description

General description

Anti-LMTK2 antibody detects endogenous levels of total LMTK2 protein.

Lemur tyrosine kinase 2 (LMTK2) is a serine/threonine kinase, located in endosomal compartments. It is also termed as BREK (brain-enriched kinase), AATYK-2 (apoptosis-associated tyrosine kinase 2), cdk5, KPI-2 and Cprk. It is expressed at high levels in the plasma membrane. LMTK2 consists of 1503 amino acids and is located on human chromosome 7q21.

Immunogen

The antiserum was produced against synthesized peptide derived from human LMTK2.

Immunogen Range: 651-700

Application

Anti-LMTK2 antibody has been used in western blotting.

Biochem/physiol Actions

Lemur tyrosine kinase 2 (LMTK2) participates in endosomal membrane trafficking and neuronal physiology. It also participates in the differentiation of tissues and acts as a negative regulator of nerve growth factor (NGF)-induced neuronal differentiation.

Features and Benefits

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Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: nwg
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable