SAB4301137
Anti-ACTIN antibody produced in rabbit
affinity isolated antibody
Synonym(s):
ACTB
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
42 kDa
species reactivity
plant
concentration
1 mg/mL
technique(s)
western blot: 1:500-1:2000 (Cell Lysate)
isotype
IgG
accession no.
NP_190236.1
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
Arabidopsis thaliana ... ACT12(823805)
General description
Actin/ actin β(ACTB) is encoded by the gene mapped to human chromosome 7p15-p12. In mammals, actin protein consists of six different isoforms encoded by separate genes. The four isoforms αskeletal-actin, αcardiac-actin, αsmooth-actin, and γ smooth-actin are expressed in skeletal, cardiac and smooth muscle. The other two isoforms, β cyto-actin and γ cyto-actin are ubiquitously expressed.
Specificity
The antibody detects endogenous levels of total ACTIN protein.
Immunogen
Synthetic peptide corresponding to residues near the N terminal of Arabidopsis thaliana actin
Biochem/physiol Actions
Actin plays a vital role in various cellular processes, such as cell division, migration, junction formation, chromatin remodeling, transcriptional regulation, vesicle trafficking, and cell shape regulation. Polymorphism in the smooth muscle α-actin (ACTA2) is associated with the development of thoracic aortic aneurysms and dissections.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Not finding the right product?
Try our Product Selector Tool.
recommended
Product No.
Description
Pricing
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Customers Also Viewed
Sublocalization of an invasion-inducing locus and other genes on human chromosome 7.
Habets G G M, et al.
Cytogenetic and genome research, 60(3-4), 200-205 (1992)
Mutations in smooth muscle ?-actin (ACTA2) lead to thoracic aortic aneurysms and dissections.
Guo D C, et al.
Nature Genetics, 39(12), 1488-1488 (2007)
Bo Zeng et al.
Nature communications, 8(1), 1920-1920 (2017-12-06)
Impaired albumin reabsorption by proximal tubular epithelial cells (PTECs) has been highlighted in diabetic nephropathy (DN), but little is known about the underlying molecular mechanisms. Here we find that ORAI1-3, are preferentially expressed in PTECs and downregulated in patients with DN.
Dong Meng et al.
The Plant journal : for cell and molecular biology, 106(5), 1278-1297 (2021-03-19)
Calcineurin B-like (CBL)-interacting protein kinases (CIPKs) play a central role in Ca2+ signalling and promote drought tolerance in plants. The CIPK gene family in pigeon pea (Cajanus cajan L.), a major food crop affected by drought, has not previously been
Chuan-Jin Wu et al.
The Journal of clinical investigation, 127(2), 623-634 (2017-01-18)
Congenital tufting enteropathy (CTE) is a severe autosomal recessive human diarrheal disorder with characteristic intestinal epithelial dysplasia. CTE can be caused by mutations in genes encoding EpCAM, a putative adhesion molecule, and HAI-2, a cell surface protease inhibitor. A similar
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service