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Key Documents

SAB2104536

Sigma-Aldrich

Anti-U2AF1, (N-terminal) antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-DKFZp313J1712, Anti-FP793, Anti-RN, Anti-RNU2AF1, Anti-U2AF35

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

28 kDa

species reactivity

dog, bovine, human, mouse, horse, rat, guinea pig, rabbit

concentration

0.5 mg - 1 mg/mL

technique(s)

western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... U2AF1(7307)

Related Categories

General description

The previously assigned protein identifier Q701P4 has been merged into Q01081. Full details can be found on the UniProt database.

Immunogen

Synthetic peptide directed towards the N terminal region of human U2AF1

Biochem/physiol Actions

This gene belongs to the splicing factor SR family of genes. U2 auxiliary factor, comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the small subunit which pl

Sequence

Synthetic peptide located within the following region: MAEYLASIFGTEKDKVNCSFYFKIGACRHGDRCSRLHNKPTFSQTILIQN

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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U2AF1 mutations alter splice site recognition in hematological malignancies.
Ilagan JO
Genome Research, 25(1), 14-26 (2015)
Recurrent mutations in the U2AF1 splicing factor in myelodysplastic syndromes.
Graubert TA
Nature Genetics, 44(1), 53-57 (2011)
Kinetic competition during the transcription cycle results in stochastic RNA processing.
Coulon A
eLife, 3, 1-22 (2014)

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