RAB0631
Human C5a / Complement C5a ELISA Kit
for serum, plasma, and cell culture supernatants
Synonym(s):
Complement C5a
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About This Item
UNSPSC Code:
41116158
NACRES:
NA.32
Recommended Products
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
input
sample type plasma
sample type cell culture supernatant(s)
sample type serum
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 31 pg/mL
standard curve range: 31.25-2000 pg/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... C5(727)
General description
Human complement 5a (C5a) is generated during complement activation from the α-chain of complement C5. It binds to a signaling G-protein coupled receptor (GPCR), inducing neutrophil chemotaxis and endothelial cell activation. C5a also triggers an oxidative burst in macrophages and neutrophils and induces release of histamine in basophils and mast cells.
The antibody pair provided in this kit recognizes human Complement Component C5a.
Application
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
Kit Components Also Available Separately
Product No.
Description
SDS
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Met. Corr. 1
Storage Class Code
8A - Combustible corrosive hazardous materials
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Immune Responses to Biosurfaces: Mechanisms and Therapeutic Interventions (2015)
Cynthia Owsley et al.
Investigative ophthalmology & visual science, 55(8), 4776-4789 (2014-05-24)
Delayed rod-mediated dark adaptation (DA) is characteristic of early age-related macular degeneration (AMD) and also can be observed in some older adults in normal macular health. We examine cross-sectional associations between rod-mediated DA and risk factors for AMD in older
New developments in C5a receptor signaling
Sarma J V and Peter A W
Cell health and cytoskeleton, 4, 73-82 (2012)
Complement System Part II: Role in Immunity
Nicolas S M, et al.
Frontiers in Immunology, 6, 257-257 (2015)
Molecular and expression analysis of complement component C5 in the nurse shark (Ginglymostoma cirratum) and its predicted functional role.
Matthew G, et al.
Fish & Shellfish Immunology, 27(1), 40-49 (2009)
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