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N217

Sigma-Aldrich

Anti-Nitric Oxide Synthase, Universal antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

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About This Item

MDL number:
MFCD01324876
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

200

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

mouse, bovine, rat, human, pig

technique(s)

immunohistochemistry (frozen sections): 1:100
western blot: 1:1,000

UniProt accession no.

P29474

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... NOS1(4842) , NOS2(4843) , NOS3(4846)
mouse ... Nos1(18125) , Nos2(18126)
rat ... Nos1(24598) , Nos2(24599)

Immunogen

synthetic peptide (Asp-Gln-Lys-Arg-Tyr-His-Glu-Asp-Ile-Phe-Gly), derived from amino acids 1113-1122 with N-terminally added Asp, of mouse iNOS and nNOS. The immunogen sequence is highly conserved among the various NOS isoforms.

Physical form

Solution in phosphate buffered saline, containing 1 mg/ml bovine serum albumin and 0.05% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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K Somersalo et al.
The Journal of biological chemistry, 270(15), 8629-8636 (1995-04-14)
Intracellular adhesion molecule-2 (ICAM-2), one of the ligands of CD11a/CD18 (LFA-1), is mainly expressed on endothelial and hematopoietic cells. The biological significance of ICAM-2 has remained unclear. Previous findings have shown that a peptide from ICAM-2, spanning residues 21-42 from
L L Thomsen et al.
Cancer research, 54(5), 1352-1354 (1994-03-01)
Nitric oxide is generated by the NO synthases, a family of isoenzymes expressed in a wide range of mammalian cells. In the vascular and nervous systems distinct isoforms generate NO to act as a signal transduction mechanism. The isoform induced
Sumiharu Nagaoka et al.
Insect biochemistry and molecular biology, 84, 40-47 (2017-04-18)
A trypsin-like protease called initiatorin is known to initiate sperm motility in the silkworm, Bombyx mori, but little is known about the signaling events leading to sperm flagellar beating. The aim of this study was to investigate whether this mechanism
A Amaroli et al.
European journal of histochemistry : EJH, 56(4), e47-e47 (2013-01-31)
In Dictyostelium discoideum (D. discoideum), compounds generating nitric oxide (NO) inhibit its aggregation and differentiation without altering cyclic guanosine monophosphate (cGMP) production. They do it by preventing initiation of cyclic adenosine monophosphate (cAMP) pulses. Furthermore, these compounds stimulate adenosine diphosphate

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