I2511
IgG from human serum
reagent grade, ≥95% (HPLC), buffered aqueous solution
Synonym(s):
Human IgG
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About This Item
conjugate
unconjugated
grade
reagent grade
Assay
≥95% (HPLC)
form
buffered aqueous solution
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
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General description
IgG antibody subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defence of the neonate against infections
Human IgG is purified from normal human serum by precipitation and gel filtration techniques.
Human IgG is purified from normal human serum by precipitation and gel filtration techniques.
Application
Purified human IgG has been used :-
- as blocking antibody for flow cytometry
- as negative control in chromatin immunoprecipitation assays
- to precipitate IgG in human larynx epidermoid carcinoma cells by immunoprecipitation
- as a standard in enzyme-linked immunosorbent assay
Biochem/physiol Actions
Immunoglobulin G (IgG) regulates the immune responses such as phagocytosis and is also involved in the development of autoimmune diseases. IgG1 regulates complement fixation in mice.
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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