234A-1

hCG Rabbit Polyclonal Antibody

• UNSPSC Code: 12352200
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100; 500
• conjugate: unconjugated
• antibody form: Ig fraction of antiserum
• antibody product type: primary antibodies
• clone: polyclonal
• description: For In Vitro Diagnostic Use in Select Regions (See Chart)
• form: buffered aqueous solution
• species reactivity: human
• packaging: vial of 0.1 mL concentrate (234A-14); vial of 0.5 mL concentrate (234A-15); bottle of 1.0 mL predilute (234A-17); vial of 1.0 mL concentrate (234A-16); bottle of 7.0 mL predilute (234A-18)
• manufacturer/tradename: Cell Marque^™
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:250
• control: placenta
• shipped in: wet ice
• storage temp.: 2-8°C
• visualization: cytoplasmic
• Gene Information: human ... NUP42(11097)

Description

General description

Human chorionic gonadotropin (hCG) is a hormone synthesized by syncytiotrophoblasts and belongs to a group of glycoprotein hormones known as gonadotropins. Gonadotropins regulate normal growth, sexual development, and reproductive function. This antibody detects syncytiotrophoblasts in placenta and in tumors such as choriocarcinoma and some cases of seminoma.
hCG is a protein secreted in large quantities by normal trophoblasts; the antibody detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive for anti-hCG. hCG expression by non-trophoblastic tumors may indicate aggressive behavior since it has been observed that hCG may play a role in the host response to a given tumor.

Quality

IVD

IVD

IVD

RUO

Linkage

hCG Positive Control Slides, Product No. 234S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany