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D7770

Supelco

Diminazene aceturate

analytical standard

Synonym(s):

Berenil

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About This Item

Empirical Formula (Hill Notation):
C14H15N7 · 2C4H7NO3
CAS Number:
908-54-3
Molecular Weight:
515.52
EC Number:
212-999-2
MDL number:
MFCD00058386
UNSPSC Code:
41116107
PubChem Substance ID:
329798786

grade

analytical standard

Quality Level

200

form

powder

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

CC(=O)NCC(O)=O.CC(=O)NCC(O)=O.NC(=N)c1ccc(N\N=N\c2ccc(cc2)C(N)=N)cc1

InChI

1S/C14H15N7.2C4H7NO3/c15-13(16)9-1-5-11(6-2-9)19-21-20-12-7-3-10(4-8-12)14(17)18;2*1-3(6)5-2-4(7)8/h1-8H,(H3,15,16)(H3,17,18)(H,19,20);2*2H2,1H3,(H,5,6)(H,7,8)

InChI key

OKQSSSVVBOUMNZ-UHFFFAOYSA-N

Related Categories

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
SLCJ6075
SLCC4319
SLBZ7521
SLBW5487
SLBS6137

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Jia Yu Peppermint Lee et al.
British journal of pharmacology, 175(12), 2204-2218 (2017-11-15)
Acid-sensing ion channels (ASICs) are primary acid sensors in mammals, with the ASIC1b and ASIC3 subtypes being involved in peripheral nociception. The antiprotozoal drug diminazene is a moderately potent ASIC inhibitor, but its analgesic activity has not been assessed. We
M Gysin et al.
International journal for parasitology. Drugs and drug resistance, 8(2), 159-164 (2018-03-28)
Trypanosoma congolense is a protozoan parasite that is transmitted by tsetse flies, causing African Animal Trypanosomiasis, also known as Nagana, in sub-Saharan Africa. Nagana is a fatal disease of livestock that causes severe economic losses. Two drugs are available, diminazene
A Sow et al.
Veterinary parasitology, 187(1-2), 105-111 (2012-01-24)
A longitudinal study assessed the chemoresistance to isometamidium chloride (ISM) and diminazene aceturate (DA) in the region of the Boucle du Mouhoun in Burkina Faso. A preliminary cross-sectional survey allowed the identification of the 10 villages with the highest parasitological
Vinayak Shenoy et al.
American journal of respiratory and critical care medicine, 187(6), 648-657 (2013-02-02)
Studies have demonstrated that angiotensin-converting enzyme 2 (ACE2) plays a protective role against lung diseases, including pulmonary hypertension (PH). Recently, an antitrypanosomal drug, diminazene aceturate (DIZE), was shown to exert an "off-target" effect of enhancing the enzymatic activity of ACE2
Raqueli T França et al.
Veterinary clinical pathology, 42(1), 31-39 (2013-03-06)
Rangelia vitalii is a tick-transmitted piroplasm that causes both hemolytic and hemorrhagic disease in dogs in Brazil. The aim of this study was to evaluate the response of the bone marrow in dogs experimentally infected with R vitalii during the
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