8.20116

Azelaic acid,

technical grade for synthesis

• Synonym(s): Azelaic acid,, Nonanedioic acid
• Linear Formula: HOOC(CH₂)₇COOH
• CAS Number: 123-99-9
• Molecular Weight: 188.22
• MDL number: MFCD00004432
• UNSPSC Code: 12352106
• EC Index Number: 204-669-1

Properties

• vapor pressure: <1 hPa ( 20 °C)
• Quality Level: 200
• Assay: ≥90.0% (GC)
• form: crystals
• potency: >4000 mg/kg LD₅₀, oral (Rat); >10 g/kg LD₅₀, skin (Rat)
• pH: 3.5 (1 g/L in H₂O)
• bp: 237 °C/20 hPa
• mp: 107 °C
• transition temp: flash point 215 °C
• density: 1.029 g/cm³ at 20 °C
• storage temp.: 2-30°C
• InChI: 1S/C9H16O4/c10-8(11)6-4-2-1-3-5-7-9(12)13/h1-7H2,(H,10,11)(H,12,13)
• InChI key: BDJRBEYXGGNYIS-UHFFFAOYSA-N

Description

Application

• Enhancing Oxidative Stability in Fish Cooking Wastewater: Azelaic acid was studied for its effectiveness in treating fish cooking wastewater to enhance the oxidative stability of polyunsaturated fatty acids, demonstrating its potential in reducing environmental impact and improving wastewater treatment processes (Araújo-Rodrigues et al., 2024).
• Comprehensive Review of Azelaic Acid: A detailed review of azelaic acid, covering its synthesis, properties, and a broad spectrum of applications, particularly highlighting its role in dermatology and industrial manufacturing processes, serving as a foundational reference for both academic research and industrial applications (2006).
• Advancements in Hydrogel Microneedles for Cancer Treatment: Investigates the use of azelaic acid in the fabrication of hydrogel microneedles for melanoma treatment, emphasizing its role in improving delivery systems for targeted therapy and enhancing treatment efficacy (Xing et al., 2024).
• Dermatological Applications of Azelaic Acid: Explores the diverse uses of azelaic acid in dermatology, including its mechanisms of action against acne and hyperpigmentation, and its formulation in various dermatological products, highlighting its therapeutic potential and versatility in skin treatment regimens (Sauer et al., 2023).
• Gut Microbiota-related Metabolite Studies: Discusses azelaic acid′s role in mitigating intestinal inflammation associated with oral infections, demonstrating its importance in the study of gut microbiota-related metabolites and their potential in treating infectious diseases (Yang et al., 2023).

Analysis Note

Assay (GC, area%): ≥ 90.0 % (a/a)
Identity (IR): passes test

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315 - H319
• Precautionary Statements: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): 419.0 °F
• Flash Point(C): 215 °C