Skip to Content
Merck
All Photos(1)

Key Documents

More Documents

749613

Sigma-Aldrich

4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium tetrafluoroborate

97%

Synonym(s):

DMTMM, MMTM

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C10H17BF4N4O3
Molecular Weight:
328.07
MDL number:
MFCD11045040
UNSPSC Code:
12352005
PubChem Substance ID:
329766006
NACRES:
NA.22

Assay

97%

form

solid

mp

202-207 °C

SMILES string

F[B-](F)(F)F.COc1nc(OC)nc(n1)[N+]2(C)CCOCC2

InChI

1S/C10H17N4O3.BF4/c1-14(4-6-17-7-5-14)8-11-9(15-2)13-10(12-8)16-3;2-1(3,4)5/h4-7H2,1-3H3;/q+1;-1

InChI key

LCRXDNPNQMIQFZ-UHFFFAOYSA-N

Application

4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium tetrafluoroborate (DMTMM BF4) can be used as a coupling reagent alternative to DMTMM Cl in peptide synthesis because of its stability. It is also used in the synthesis of:
  • Esters and peptides in both solution and solid-phase.
  • γ-aminobutyric acid (GABA)-containing cyclic heptapeptide, unguisin A.
  • The cyclization of linear tetrapeptides.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H315,H319,H335

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

George Lo Huang et al.
Nanomaterials (Basel, Switzerland), 9(5) (2019-05-12)
Indoleamine 2,3-dioxygenase (IDO) is an immunomodulating enzyme that is overexpressed in many cancers with poor prognosis. IDO suppresses T cell immunity by catabolizing tryptophan into kynurenine (KYN), which induces apoptosis in T effector cells and enhances T regulatory cells, providing
Xiaoqin Zhang et al.
Carbohydrate polymers, 247, 116749-116749 (2020-08-25)
To enhance the drug delivery efficiency of hyaluronic acid (HA), we designed and prepared glycodendron and pyropheophorbide-a (Ppa)-functionalized HA (HA-Ppa-Dendron) as a nanosystem for cancer photodynamic therapy. Linear Ppa-modified HA (HA-Ppa) was also prepared as a control. Cellular uptake of
An improved process for the synthesis of DMTMM-based coupling reagents
Raw SA
Tetrahedron Letters, 50(8), 946-948 (2009)
Total synthesis of unguisin A
Hunter L and Chung JH
The Journal of Organic Chemistry, 76(13), 5502-5505 (2011)
Maria Laura Alfieri et al.
Antioxidants (Basel, Switzerland), 9(3) (2020-03-22)
The ability of gelatin-based hydrogels of incorporating and releasing under controlled conditions 5,6-dihydroxyindole-2-carboxylic acid (DHICA), a melanin-related metabolite endowed with marked antioxidant properties was investigated. The methyl ester of DHICA, MeDHICA, was also tested in view of its higher stability
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service