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Key Documents

470058

Sigma-Aldrich

D-Tyrosinol hydrochloride

98%

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About This Item

Linear Formula:
4-(HO)C6H4CH2CH(NH2)CH2OH · HCl
CAS Number:
Molecular Weight:
203.67
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

98%

optical activity

[α]22/D +18°, c = 1 in H2O

reaction suitability

reaction type: solution phase peptide synthesis

mp

161-165 °C (lit.)

application(s)

peptide synthesis

SMILES string

Cl[H].N[C@@H](CO)Cc1ccc(O)cc1

InChI

1S/C9H13NO2.ClH/c10-8(6-11)5-7-1-3-9(12)4-2-7;/h1-4,8,11-12H,5-6,10H2;1H/t8-;/m1./s1

InChI key

PNGCRFWYSRUQTB-DDWIOCJRSA-N

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Eric T Larson et al.
Journal of molecular biology, 409(2), 159-176 (2011-03-23)
The single tyrosyl-tRNA synthetase (TyrRS) gene in trypanosomatid genomes codes for a protein that is twice the length of TyrRS from virtually all other organisms. Each half of the double-length TyrRS contains a catalytic domain and an anticodon-binding domain; however
C Monteilhet et al.
Journal of molecular biology, 173(4), 477-485 (1984-03-15)
Crystalline complexes of tyrosyl-tRNA synthetase from Bacillus stearothermophilus were prepared with adenosine, AMP, ATP and PPi, all in the presence of tyrosinol, which binds strongly to the tyrosine binding site but cannot be adenylated by ATP. The hydrolysis of ATP
M Angeles Gilabert et al.
Biological chemistry, 385(12), 1177-1184 (2005-01-18)
We report here on the stereospecificity observed in the action of horseradish peroxidase (HRPC) on monophenol and diphenol substrates. Several enantiomers of monophenols and o-diphenols were assayed: L-tyrosinol, D-tyrosinol, L-tyrosine, DL-tyrosine, D-tyrosine, L-dopa, DL-dopa, D-dopa, L-alpha-methyldopa, DL-alpha-methyldopa, DL-adrenaline, D-adrenaline, L-isoproterenol
E M Newman et al.
Cancer research, 43(10), 4703-4708 (1983-10-01)
The effects of amino acid deprivation and treatment with amino alcohols upon the growth, viability, and susceptibility to methotrexate (MTX) cytotoxicity were examined in BALB/3T3 cells and their virally transformed counterparts, SV-T2 cells. Cells were deprived of either histidine or

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