440140

(3-Aminopropyl)triethoxysilane

99%

• Synonym(s): 3-Triethoxysilylpropylamine, APTES, APTS
• Linear Formula: H₂N(CH₂)₃Si(OC₂H₅)₃
• CAS Number: 919-30-2
• Molecular Weight: 221.37
• Beilstein: 1754988
• EC Number: 213-048-4
• MDL number: MFCD00008207
• UNSPSC Code: 12352103
• PubChem Substance ID: 24867571
• NACRES: NA.23

Properties

• Assay: 99%
• form: liquid
• bp: 217 °C/760 mmHg (lit.)
• density: 0.946 g/mL at 25 °C (lit.)
• SMILES string: CCO[Si](CCCN)(OCC)OCC
• InChI: 1S/C9H23NO3Si/c1-4-11-14(12-5-2,13-6-3)9-7-8-10/h4-10H2,1-3H3
• InChI key: WYTZZXDRDKSJID-UHFFFAOYSA-N

Description

General description

(3-Aminopropyl)tiethoxysilane (APTES) is used as an amino-silane which is mainly used as a dispersant. APTES attaches an amino group to the functional silane for bio-conjugation.

Application

Forms aminopropyl derivative of glass, an adsorbent for affinity chromatography. Used to prepare positively charged slides suitable for use with various immunohistochemical and in situ hybridization procedures. Recently (3-Aminopropyl)triethoxysilane has been used to prepare dye-doped silica nanoparticles with minimal aggregation and minimal nonspecific binding with biomolecules.

Self-assembled monolayer (SAM) of APTES can be used to improve the adhesion of graphene flakes and SiO₂ to enable better contact with the metal electrodes. These electrodes may be used as electro-responsive tools for bio-sensing applications. It can be used to functionalize silane diazirine for fiber optic biosensor application. Hollow microcarriers (HMCs) can be surface modified with APTES which may be used for regenerative medicines and recombinant cells in biopharmaceutical industries.

Used in a preparation of a series of tenary composite films of polyimide/SiO/polydiphenylsiloxane with good optical transparency.

Safety Information

• Pictograms: GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H302,H314,H317
• Precautionary Statements: P261 - P272 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 1
• Flash Point(F): 199.4 °F - closed cup
• Flash Point(C): 93 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves