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238813

Sigma-Aldrich

(±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid

97%

Synonym(s):

Trolox

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About This Item

Empirical Formula (Hill Notation):
C14H18O4
CAS Number:
53188-07-1
Molecular Weight:
250.29
Beilstein:
1384051
EC Number:
258-422-8
MDL number:
MFCD00006846
UNSPSC Code:
12352100
PubChem Substance ID:
24854347
NACRES:
NA.22

Quality Level

200

Assay

97%

storage condition

under inert gas

mp

187-189 °C (lit.)

storage temp.

2-8°C

SMILES string

Cc1c(C)c2OC(C)(CCc2c(C)c1O)C(O)=O

InChI

1S/C14H18O4/c1-7-8(2)12-10(9(3)11(7)15)5-6-14(4,18-12)13(16)17/h15H,5-6H2,1-4H3,(H,16,17)

InChI key

GLEVLJDDWXEYCO-UHFFFAOYSA-N

Gene Information

rat ... Akr1b1(24192)

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General description

(±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid (Trolox) exhibits radical scavenging and antioxidant activities.

Application

(±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid (Trolox) has been used in 6-hydroxy-2,5,7,8-tetramethyl chromane-2-carboxylic acid equivalent antioxidant assay (TEAC) to determine the total antioxidant capacity of different fruit species.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Legal Information

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Gláucia E M L Siervo et al.
Biology of reproduction, 100(1), 112-122 (2018-07-17)
Spermatogenesis and steroidogenesis are not fully established during puberty. Especially during this period, children and adolescents may be chronically sleep deprived due to early school hours and constant exposure to artificial light and interactive activities. We have previously shown that
R Lakshmi Sundaram et al.
Journal of ethnopharmacology, 241, 111962-111962 (2019-05-24)
Spermacoce hispida (S.hispida), a potential medicinal plant has been traditionally used as an antibacterial, antieczemic, antihypertensive, antidiabetic and antihyperlipidemic agent. Although, this plant has been claimed to protect against oxidative injury and inflammatory conditions in recent studies, its cardioprotective effect
Miguel Á Sánchez-Madrigal et al.
Foods (Basel, Switzerland), 8(7) (2019-07-25)
Effects of agave fructans as carrier agents on the encapsulation of blue corn anthocyanins using spray-drying were evaluated. Blue corn extract was mixed with 6%, 8%, 10%, and 12% (w/v) of agave fructans in duplicate and dried at 150 °C.
C Giulivi et al.
Archives of biochemistry and biophysics, 303(1), 152-158 (1993-05-15)
The reactivity of Trolox C, a water-soluble analog of vitamin E, toward protein radicals formed during the oxidation of metmyoglobin and the therefrom derived molecular products was examined in terms of the ability of the phenolic antioxidant to prevent specific
D A Kirke et al.
Food chemistry, 221, 1104-1112 (2016-12-17)
Due to their high anti-oxidant activity, phlorotannins represent potential natural alternatives to synthetic preservatives currently used within the food industry. However, their successful integration into food products requires research into their chemical integrity, particularly when selecting appropriate storage conditions. Subsequently
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