GRIN2B
glutamate receptor, ionotropic, N-methyl D-aspartate 2B
Synonyms:
GluN2B, MRD6, NMDAR2B, NR2B, hNR3
Species:
Human GRIN2B (2904), Mouse Grin2b (14812), Rat Grin2b (24410), chicken GRIN2B (417965), dog GRIN2B (494009), domestic cat GRIN2B (101094356), Horse GRIN2B (100063746), cow GRIN2B (537804), domestic guinea pig Grin2b (100731840), naked mole-rat Grin2b (101723091)
UniProtKB ID:
Gene ID:
- Human(2904) Summary: N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain. [provided by RefSeq, Jul 2008]
- Mouse(14812) glutamate receptor, ionotropic, NMDA2B (epsilon 2)
- Rat(24410) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
- chicken(417965) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
- dog(494009) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
- domestic cat(101094356) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
- Horse(100063746) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
- cow(537804) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
- domestic guinea pig(100731840) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
- naked mole-rat(101723091) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
- sheep(101118179) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
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Small Molecule - Agonist
Product Number
Description
Species
Small Molecule - Allosteric Modulator
Product Number
Description
Species
Acamprosate calcium, United States Pharmacopeia (USP) Reference Standard, monograph mol wt. 400.48 (C10H20CaN2O8S2),
Species
human
Small Molecule - Antagonist
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-phospho-GRIN2B (pSer1303) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
western blot
Anti-GRIN2B (Ab-1474) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
Anti-phospho-GRIN2B (pTyr1474) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
Monoclonal Anti-GRIN2B antibody produced in mouse, clone 2G5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
proximity ligation assay
western blot
proximity ligation assay
western blot
PhosphoDetect Anti-NMDA NR2B (pTyr¹⁴⁷²) Rabbit pAb, liquid, Calbiochem®,
Species Reactivity
rat
Application
Small Molecule - Blocker
Product Number
Description
Species
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
Species
human
Small Molecule - Inhibitor
Product Number
Description
Species
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
Species
human