SAB4500758

Anti-PIP5K antibody produced in rabbit

affinity isolated antibody

• Synonym(s): 1- phosphatidylinositol-4-phosphate 5-kinase, FYV1, FYVE finger-containing phosphoinositide kinase, KIAA0981, PIKfyve
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 237 kDa
• species reactivity: mouse, human
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:5000; immunofluorescence: 1:100-1:500; western blot: 1:500-1:1000
• NCBI accession no.: Q9Y2I7
• UniProt accession no.: Q9Y2I7
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... PIKFYVE(200576)

Description

General description

PIKFYVE belongs to an evolutionarily ancient gene family of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2)enzymes. PIKFYVE gene is located on human chromosome 2q34. Anti-PIP5K antibody detects endogenous levels of total PIP5K protein.

Immunogen

The antiserum was produced against synthesized peptide derived from human PIP5K.

Immunogen Range: 71-120

Biochem/physiol Actions

Phosphatidylinositol 4-phosphate 5-kinase (PIP5K)/Phosphoinositide kinase, FYVE-type zinc finger containing (PIKFYVE) protein plays a key role in phosphoinositide 5-kinase and protein kinase activity. It is essential for post-Golgi vesicle processing. Mutation in the PIKFYVE gene is associated with fleck corneal dystrophy (FCD).

Features and Benefits

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Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: nwg
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable