M8631

Melanin

Synthetic

• CAS Number: 8049-97-6
• EC Number: 232-473-6
• MDL number: MFCD00131581
• UNSPSC Code: 12352204
• NACRES: NA.83

Properties

• Quality Level: 100
• form: powder
• storage temp.: −20°C
• InChI: 1S/C18H10N2O4/c1-5-13-9-7(3-19-13)12-10-8(11(9)17(23)15(5)21)4-20-14(10)6(2)16(22)18(12)24/h3-4,19-20H,1-2H3
• InChI key: XUMBMVFBXHLACL-UHFFFAOYSA-N

Description

General description

Melanin is a vital pigment present on the surface structures of vertebrates, which contribute to skin color. It has three forms such as, eumelanin, pheomelanin and neuromelanin. Melanin has cation chelating and redox properties. It is a potent absorbent of light. Melanin functions as a chemoprotective and photoprotective pigment. Mutations in this gene are associated with oculocutaneous albinism, vitiligo, piebaldism and Waardenburg syndrome.

Application

Melanin has been used:

• in spectrophotometry
• to study its effect on reverse transcription polymerase chain reaction (RT-PCR) inhibition and effect of BSA (bovine serum albumin) in overcoming the inhibition
• as an absorber for skin layer in near-infrared tissue spectra
• Raman spectroscopy

Preparation Note

Prepared by oxidation of tyrosine with hydrogen peroxide.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves