I1625

3-Indoleacrylic acid

powder

• Synonym(s): 3-(3-Indolyl)acrylic acid, IAA
• Empirical Formula (Hill Notation): C₁₁H₉NO₂
• CAS Number: 1204-06-4
• Molecular Weight: 187.19
• Beilstein: 6317
• EC Number: 214-872-7
• MDL number: MFCD00005633
• UNSPSC Code: 12352106
• PubChem Substance ID: 24895938
• NACRES: NA.52

Properties

• grade: for molecular biology
• Assay: ≥98.0% (HPLC); ≥98.0% (TLC)
• form: powder
• mol wt: 187.19 g/mol
• storage temp.: room temp
• SMILES string: OC(=O)\C=C\c1c[nH]c2ccccc12
• InChI: 1S/C11H9NO2/c13-11(14)6-5-8-7-12-10-4-2-1-3-9(8)10/h1-7,12H,(H,13,14)/b6-5+
• InChI key: PLVPPLCLBIEYEA-AATRIKPKSA-N

Description

General description

3-Indoleacrylic acid (IAA) is a chemical used for the induction of gene transcription. This expression system requires that the gene of interest is cloned in plasmids containing the trpE promoter.

Application

Suitable for induction of gene transcription in systems controlled by the trpE promoter.

Biochem/physiol Actions

3-Indoleacrylic acid helps to block the mycelial growth of Neurospora crassa. As a result, the cells accumulate indoleglycerol phosphate, which influences the rate of tryptophan synthetase.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves