C8755

L-Cystine

≥98% (TLC)

• Synonym(s): (R,R)-3,3′-Dithiobis(2-aminopropionicacid)
• Linear Formula: [-SCH₂CH(NH₂)CO₂H]₂
• CAS Number: 56-89-3
• Molecular Weight: 240.30
• Beilstein: 1728094
• EC Number: 200-296-3
• MDL number: MFCD00064228
• UNSPSC Code: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 24893101
• NACRES: NA.26

Properties

• product name: L-Cystine, ≥98% (TLC), crystalline
• Assay: ≥98% (TLC)
• form: crystalline
• color: white to off-white
• mp: >240 °C (dec.) (lit.)
• solubility: 1 M HCl: 50 mg/mL, clear, colorless to faintly yellow
• application(s): cell analysis; peptide synthesis
• storage temp.: room temp
• SMILES string: N[C@@H](CSSC[C@H](N)C(O)=O)C(O)=O
• InChI: 1S/C6H12N2O4S2/c7-3(5(9)10)1-13-14-2-4(8)6(11)12/h3-4H,1-2,7-8H2,(H,9,10)(H,11,12)/t3-,4-/m0/s1
• InChI key: LEVWYRKDKASIDU-IMJSIDKUSA-N

Description

Application

L-Cystine has been used in in vitro cystine solubility assay to identify potential drugs that influence cystine solubility. It is also used as a supplement of phosphate-buffered saline to slice and wash periprosthetic tissues.

Biochem/physiol Actions

Cysteine is the source of disulfide linkages in proteins and has a role in sulfur transport. It undergoes rapid oxidation to form cystine at physiological pH. L-cystine is crucial for oxygen production and low density lipoprotein modification by arterial smooth muscle cells. It also has a role in the synthesis of glutathione.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves