B0311

Bmx Active human

recombinant, expressed in E. coli, ≥85% (SDS-PAGE), buffered aqueous glycerol solution

• Synonym(s): Bone Marrow Kinase X-Linked
• MDL number: MFCD07370635
• UNSPSC Code: 12352200
• NACRES: NA.32

Properties

• recombinant: expressed in E. coli
• Quality Level: 200
• Assay: ≥85% (SDS-PAGE)
• form: buffered aqueous glycerol solution
• specific activity: ≥10 units/mg protein
• mol wt: ~110 kDa
• UniProt accession no.: P51813
• shipped in: dry ice
• storage temp.: −70°C
• Gene Information: human ... BMX(660)

Description

Biochem/physiol Actions

The BMX gene encodes a novel non-receptor tyrosine kinase, which may play a role in the growth and differentiation of hematopoietic cells. Bmx induces the activation of the Stat-signaling pathway.

Unit Definition

Kinase activity is measured as the molar amount of phosphate incorporated into Poly Glu-Tyr substrate per minute per mg protein at 30 °C using a final concentration of 50 μM [³²P]-ATP.

Physical form

Solution of 50 μL in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, and 30% glycerol.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves