61760
Lectin from Canavalia ensiformis
lyophilized, ≥50% (GE), powder
Synonym(s):
Agglutinin from jack beans, Con A
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About This Item
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biological source
Canavalia ensiformis
form
powder
quality
lyophilized
mol wt
Mr ~53000
concentration
≥50% (GE)
technique(s)
XRF: suitable
storage temp.
2-8°C
Biochem/physiol Actions
Con A is not blood group specific but has an affinity for terminal α-D-mannosyl and α-D-glucosyl residues. Ca2+ and Mn2+ ions are required for activity. Con A dissociates into dimers at pH 5.6 or below. Between pH 5.8 and pH 7.0, Con A exists as a tetramer; above pH 7.0 higher aggregates are formed. Con A exhibits mitogenic activity which is dependent on its degree of aggregation. Succinylation results in an active dimeric form which remains a dimer above pH 5.6.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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H. Bittiger and H.P. Schnebli, eds.
Concanavalin A as a Tool, 639-639 (1976)
Lectins in the isolation of receptors on lymphocytes.
J J Marchalonis
Methods in enzymology, 150, 463-477 (1987-01-01)
Dongxu Wang et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 144, 111576-111576 (2020-08-05)
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