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18108

Sigma-Aldrich

Sodium propionate

meets analytical specification of NF, 99-100.5% (ex dried subst.)

Synonym(s):

Propionic acid sodium salt

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About This Item

Linear Formula:
CH3CH2COONa
CAS Number:
137-40-6
Molecular Weight:
96.06
Beilstein:
3566934
EC Number:
205-290-4
MDL number:
MFCD00002759
UNSPSC Code:
12164500
PubChem Substance ID:
57647711
NACRES:
NA.21

Quality Level

200

Assay

99-100.5% (ex dried subst.)

quality

meets analytical specification of NF

impurities

≤0.001% heavy metals (as Pb)
≤1% water (Karl Fischer)

mp

285-286 °C (lit.)

solubility

alcohol: soluble 1 gm in 24 ml at 25 °C
water: soluble 1 gm in 0.65 ml at 25 °C
water: soluble 1 g/mL at 25 °C

cation traces

Fe: ≤30 mg/kg
Zn: ≤10 mg/kg

application(s)

pharmaceutical (small molecule)

lipid type

saturated FAs

SMILES string

[Na+].CCC([O-])=O

InChI

1S/C3H6O2.Na/c1-2-3(4)5;/h2H2,1H3,(H,4,5);/q;+1/p-1

InChI key

JXKPEJDQGNYQSM-UHFFFAOYSA-M

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Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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The Stimulatory Effect of Sodium Butyrate and Sodium Propionate on the Development of Rumen Mucosa in the Young Calf.
E.G. Sander
Journal of Dairy Science, 42, 1600-1605 (1959)
W J Chen et al.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 175(2), 215-218 (1984-02-01)
The effects of propionate on serum and liver lipid concentrations were studied in cholesterol-fed rats. Both serum and liver cholesterol levels were significantly lower in rats fed the cholesterol-propionate diet than in rats fed the cholesterol diet without propionate. Liver
J McCarthy et al.
Gut, 52(7), 975-980 (2003-06-13)
Prophylactic efficacy against colitis following lactobacillus consumption in interleukin 10 (IL-10) knockout (KO) mice has been reported. Whether this applies equally to other probiotic strains is unknown, and the mechanism is unclear. (1) To compare the effect of feeding Lactobacillus
J E Lennox et al.
Applied and environmental microbiology, 48(5), 1031-1033 (1984-11-01)
Potassium sorbate and sodium propionate brought about a marked inhibition in the growth of Penicillium expansum and a proportionally greater inhibition in the synthesis of patulin by the mold. At inhibitor concentrations used commercially in bakery products, propionate inhibited growth
Bistra B Nankova et al.
PloS one, 9(8), e103740-e103740 (2014-08-30)
Alterations in gut microbiome composition have an emerging role in health and disease including brain function and behavior. Short chain fatty acids (SCFA) like propionic (PPA), and butyric acid (BA), which are present in diet and are fermentation products of
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