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Y0000040

Ciclopirox

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridone

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About This Item

Empirical Formula (Hill Notation):
C12H17NO2
CAS Number:
29342-05-0
Molecular Weight:
207.27
MDL number:
MFCD00599441
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

ciclopirox

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

ON1C(C2CCCCC2)=CC(C)=CC1=O

InChI

1S/C12H17NO2/c1-9-7-11(13(15)12(14)8-9)10-5-3-2-4-6-10/h7-8,10,15H,2-6H2,1H3

InChI key

SCKYRAXSEDYPSA-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Ciclopirox EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302 + H312 + H332,H319

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

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Aditya K Gupta et al.
International journal of dermatology, 42 Suppl 1, 23-27 (2003-08-05)
The most common presentation of tinea pedis (athlete's foot) is that involving the interdigital spaces. Tinea pedis interdigitalis may present as asymptomatic dermatophytosis simplex or dermatophytosis complex, which is symptomatic, with secondary bacterial infection. In the dermatophytosis complex presentation there
M Bohn et al.
Journal of the American Academy of Dermatology, 43(4 Suppl), S57-S69 (2000-10-29)
Ciclopirox is a synthetic hydroxypyridone antifungal agent. In contrast to the azoles, glucuronidation is the main metabolic pathway of ciclopirox; therefore interactions with drugs metabolized via the cytochrome P450 system are unlikely Ciclopirox is also distinct from the common systemic
Aditya K Gupta et al.
International journal of dermatology, 42 Suppl 1, 3-9 (2003-08-05)
Ciclopirox is a broad-spectrum antifungal agent that also exhibits anti-inflammatory and antibacterial activity. The lotion and cream formulations of ciclopirox are effective in many types of infection, including tinea corporis/cruris, tinea pedis, cutaneous candidiasis, pityriasis (tinea) versicolor, and seborrheic dermatitis.
Ciclopirox: an overview.
A K Gupta
International journal of dermatology, 40(5), 305-310 (2001-09-14)
Aditya K Gupta et al.
International journal of dermatology, 45(1), 66-69 (2006-01-24)
Seborrheic dermatitis is a chronic superficial fungal infection of the skin, particularly affecting sites rich in sebaceous glands. Although the precise etiology of seborrheic dermatitis is uncertain, yeasts of the genus Malassezia are known to play a causative role. Ciclopirox
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