PHR1660

Indapamide

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonym(s): Indapamide, N-(4-Chloro-3-sulfamoylbenzamido)-2-methylindoline
• Empirical Formula (Hill Notation): C₁₆H₁₆ClN₃O₃S
• CAS Number: 26807-65-8
• Molecular Weight: 365.83
• EC Number: 248-012-7
• MDL number: MFCD00079375
• UNSPSC Code: 41116107
• PubChem Substance ID: 329823538

Properties

• grade: certified reference material; pharmaceutical secondary standard
• Quality Level: 300
• Agency: traceable to BP 999; traceable to Ph. Eur. I0150000; traceable to USP 1338801
• API family: indapamide
• CofA: current certificate can be downloaded
• packaging: pkg of 1 g
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-30°C
• SMILES string: CC1Cc2ccccc2N1NC(=O)c3ccc(Cl)c(c3)S(N)(=O)=O
• InChI: 1S/C16H16ClN3O3S/c1-10-8-11-4-2-3-5-14(11)20(10)19-16(21)12-6-7-13(17)15(9-12)24(18,22)23/h2-7,9-10H,8H2,1H3,(H,19,21)(H2,18,22,23)
• InChI key: NDDAHWYSQHTHNT-UHFFFAOYSA-N
• Gene Information: human ... SLC12A3(6559)

Description

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Indapamide is a diuretic that is categorized under the family of benzothiadiazines compounds. It is an oral drug that is usually prescribed as an antihypertensive agent for patients with mild to moderate hypertension.

Application

Indapamide may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by various chromatography techniques and spectrophotometry.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Safety Information

• Pictograms: GHS08
• Signal Word: Warning
• Hazard Statements: H361d - H362
• Precautionary Statements: P202 - P260 - P263 - P264 - P270 - P308 + P313
• Hazard Classifications: Lact. - Repr. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable