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70720

Supelco

N-(1-Naphthyl)ethylenediamine dihydrochloride monomethanolate

for spectrophotometric det. of nitrate and nitrite, ≥99.0%

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About This Item

Linear Formula:
C10H7NHCH2CH2NH2 · 2HCl · MeOH
CAS Number:
Molecular Weight:
291.22
Beilstein:
3707471
MDL number:
UNSPSC Code:
12000000
PubChem Substance ID:
NACRES:
NA.21

Quality Level

Assay

≥99.0% (AT)
≥99.0%

form

crystals

quality

for spectrophotometric det. of nitrate and nitrite

technique(s)

UV/Vis spectroscopy: suitable

ign. residue

≤0.05%

mp

196-199 °C (dec.)

SMILES string

Cl.Cl.CO.NCCNc1cccc2ccccc12

InChI

1S/C12H14N2.CH4O.2ClH/c13-8-9-14-12-7-3-5-10-4-1-2-6-11(10)12;1-2;;/h1-7,14H,8-9,13H2;2H,1H3;2*1H

InChI key

YUMCJWVZLMGNTD-UHFFFAOYSA-N

General description

N-(1-Naphthyl)ethylenediamine dihydrochloride is a hygroscopic analytical reagent generally suitable for determination of drugs, pharmaceuticals with free primary aromatic amino group, sulpha drugs and local anaesthetics. It may decompose on exposure to light.

Application

N-(1-Naphthyl)ethylenediamine dihydrochloride monomethanolate may be used to study antimicrobial effects against bacteria.

Other Notes

Reagent used in the simultaneous spectrophotometric determination of nitrite and nitrate by flow injection analysis

Pictograms

Exclamation markHealth hazard

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 1

Target Organs

Eyes

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Role of Chemical and Analytical Reagents in Colorimetric Estimation of Pharmaceuticals-A Review.
Somsubhra Ghosh et al.
International Journal of Medicine and Pharmaceutical Research, 1(5), 433-445 (2013)
Glen C Ulett et al.
The Journal of infectious diseases, 191(10), 1761-1770 (2005-04-20)
Group B streptococcus (GBS; Streptococcus agalactiae) induces apoptosis of macrophages, and this may be an important mechanism GBS uses to suppress immune responses. The mechanisms whereby GBS induces apoptosis have not been identified. We studied GBS infection in murine macrophage-like
M J Ahmed et al.
Talanta, 43(7), 1009-1018 (1996-07-01)
An automatic direct spectrophotometric method for the simultaneous determination of nitrite and nitrate by flow-injection analysis has been developed. Nitrite reacts with 3-nitroaniline in the presence of hydrochloric acid (0.96-1.8 M HCl or pH 0.5-0.7) to form a diazonium cation
L A Ridnour et al.
Analytical biochemistry, 281(2), 223-229 (2000-06-28)
A method for the spectrophotometric determination of nitric oxide, nitrite, and nitrate in tissue culture media is presented. The method is based on the nitric oxide-mediated nitrosative modification of sulfanilic acid that reacts with N-(1-naphthyl)ethylenediamine dihydrochloride forming an orange-colored product
Simultaneous spectrophotometric determination of nitrite and nitrate by flow injection analysis
L. Anderson
Analytica Chimica Acta, 110, 123-123 (1979)

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