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MAB1580

Sigma-Aldrich

Anti-Oligodendrocytes Antibody, clone NS-1

ascites fluid, clone NS-1, Chemicon®

Synonym(s):

RIP

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

100

antibody form

ascites fluid

antibody product type

primary antibodies

clone

NS-1, monoclonal

species reactivity

human, hamster, rat, mouse

manufacturer/tradename

Chemicon®

technique(s)

immunocytochemistry: suitable
immunohistochemistry: suitable

isotype

IgG

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... OLIG2(10215)

Specificity

Recognizes Oligodendrocytes and their myelin sheaths. MAB1580 stains both early and mature oligodendrocites.

Immunogen

Rat olfactory bulb

Application

Detect Oligodendrocytes using this Anti-Oligodendrocytes Antibody, clone NS-1 validated for use in IC, IH.
Immunohistochemistry: 1:1000-1:200,000 on 4% paraformaldehyde fixed tissue.

Immunocytochemistry

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Neuronal & Glial Markers

Physical form

Liquid with 0.1% sodium azide.
Unpurified

Storage and Stability

Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Analysis Note

Control
Oligodendrocyte culture, Brain

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Mercedes Zurita et al.
Neuroreport, 18(16), 1713-1717 (2007-10-09)
Neural transdifferentiation of bone marrow stromal cells has been questioned, because cell fusion could explain the development of new cell types, misinterpreted as transdifferentiated cells. We performed here cocultures of bone marrow stromal cells and Schwann cells, without possibility that
K+ channel blockade impairs remyelination in the cuprizone model.
Andrzej Bacia, Robert Wollmann, Betty Soliven
Glia null
Development of functional human embryonic stem cell-derived neurons in mouse brain.
Muotri, A.R. et al.
Proceedings of the National Academy of Sciences of the USA, 102(51), 18644-18648 (2005)
Grafted lineage-restricted precursors differentiate exclusively into neurons in the adult spinal cord.
Han, Steve S W, et al.
Experimental neurology, 177, 360-375 (2002)
Cell cycle alteration and decreased cell proliferation in the hippocampal dentate gyrus and in the neocortical germinal matrix of fetuses with Down syndrome and in Ts65Dn mice.
Contestabile, Andrea, et al.
Hippocampus, 17, 665-678 (2007)
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