8.03127

Diethylene glycol monoethyl ether

for synthesis

• Synonym(s): Diethylene glycol monoethyl ether, Carbitol, 2-(2-Ethoxyethoxy)-ethanol, Ethyl diglycol
• Empirical Formula (Hill Notation): C₆H₁₄O₃
• CAS Number: 111-90-0
• Molecular Weight: 134.17
• MDL number: MFCD00002872
• UNSPSC Code: 12352104
• EC Index Number: 203-919-7

Properties

• vapor pressure: 0.13 hPa ( 20 °C)
• Quality Level: 200
• Assay: ≥98% (GC)
• form: liquid
• autoignition temp.: 204 °C
• potency: 5900-6100 mg/kg LD₅₀, oral (Rat); 8476 mg/kg LD₅₀, skin (Rabbit)
• expl. lim.: 1.8-12.2 % (v/v)
• bp: 202 °C/1013 hPa
• mp: -78 °C
• transition temp: flash point 94 °C
• density: 0.99 g/cm³ at 20 °C
• storage temp.: 2-30°C
• InChI: 1S/C6H14O3/c1-2-8-5-6-9-4-3-7/h7H,2-6H2,1H3
• InChI key: XXJWXESWEXIICW-UHFFFAOYSA-N

Description

Application

• Investigation of piroctone olamine delivery to the skin from single, binary and ternary solvent systems: This study explores the efficacy of diethylene glycol monoethyl ether as a solvent in dermatological applications, highlighting its role in enhancing skin absorption properties, which is crucial for cosmetic and pharmaceutical formulations (Tang CF, et al., 2023).


• Review of Pharmaceutical Applications of Diethylene Glycol Monoethyl Ether: This review comprehensively covers the pharmaceutical applications of diethylene glycol monoethyl ether, focusing on its solvent properties and roles in drug delivery systems, crucial for advancing drug formulation techniques (Hashemzadeh N, Jouyban A, 2022).
• Stepwise Access of Emissive Ir(III) Complexes Bearing a Multi-Dentate Heteroaromatic Chelate: Demonstrates the application of diethylene glycol monoethyl ether in the synthesis of luminescent materials, providing valuable insights for the development of optical and electronic devices in material science (Zheng Z, et al., 2022).

Analysis Note

Assay (GC, area%): ≥ 98.0 % (a/a)
Density (d 20 °C/ 4 °C): 0.987 - 0.990
Water (K. F.): ≤ 0.20 %
Peroxide (as H₂O₂): ≤ 0.05 %
Identity (IR): passes test

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): 204.8 °F - closed cup
• Flash Point(C): 96 °C - closed cup