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1.06357

SAFC

Sodium disulfite

(sodium metabisulfite), EMPROVE® ESSENTIAL, Ph. Eur., BP, JP, NF, E 223

Pharma Manufacturing

Synonym(s):

Sodium disulfite, Sodium metabisulfite, Sodium pyrosulfite, Disulfite, Pyrosulfite

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About This Item

Empirical Formula (Hill Notation):
Na2O5S2
CAS Number:
7681-57-4
Molecular Weight:
190.11
MDL number:
MFCD00167602
UNSPSC Code:
12352302
E Number:
E223
EC Index Number:
231-673-0

Agency

BP
JP
NF
Ph. Eur.

Quality Level

500

product line

EMPROVE® ESSENTIAL

form

solid

pH

3.5-5 (20 °C, 50 g/L in H2O)

mp

150 °C (decomposition)

density

2.36 g/cm3 at 20 °C

application(s)

liquid formulation
ophthalmics
pharmaceutical
semi-solid formulation
solid formulation

storage temp.

15-25°C

InChI

1S/2Na.H2O5S2/c;;1-6(2)5-7(3)4/h;;(H,1,2)(H,3,4)/q2*+1;/p-2

InChI key

LDTLADDKFLAYJA-UHFFFAOYSA-L

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our EMPROVE® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Sodium disulfite has reducing and anti-septic properties with broad range of applications in pharmaceutical, cosmetic and food industry. It is commonly used as preservative and antioxidant, especially for liquid and semi-solid application. In the food industry it is can help preserving food products and maintaining their fresh appearance.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

CorrosionExclamation mark
GHS05,GHS07

Signal Word

Danger

Hazard Statements

H302,H318

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1

Supplementary Hazards

EUH031

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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