1.06267

Sodium acetate trihydrate

for analysis EMSURE^® ACS,ISO,Reag. Ph Eur

• Synonym(s): Acetic acid sodium salt trihydrate
• Linear Formula: CH₃COONa · 3H₂O
• CAS Number: 6131-90-4
• Molecular Weight: 136.08
• Beilstein: 3732037
• MDL number: MFCD00071557
• UNSPSC Code: 12352107
• EC Index Number: 204-823-8

Properties

• grade: ACS reagent
• Quality Level: 300
• Agency: reag. ISO; reag. Ph. Eur.
• product line: EMSURE^®
• Assay: 99.0-101.0% (perchloric acid titration); 99.0-101.0% dry basis (perchloric acid titration)
• form: solid
• autoignition temp.: 1112 °F; 607 °C
• potency: 3530 mg/kg LD₅₀, oral (Rat); >10000 mg/kg LD₅₀, skin (Rabbit)
• impurities: ≤0.005% Insoluble matter; ≤0.005% Reducing substances
• loss: 39.0-40.5% loss on drying, 130 °C
• pH: 7.5-9.2 (20 °C, 50 g/L in H₂O)
• mp: 58 °C
• transition temp: flash point >250 °C (anhydrous substance)
• solubility: 613 g/L
• density: 1.42 g/cm³ at 20 °C
• bulk density: 900 kg/m³
• anion traces: chloride (Cl^-): ≤0.0005%; phosphate (PO₄^3-): ≤0.0002%; sulfate (SO₄^2-): ≤0.002%
• cation traces: Al: ≤0.0005%; As: ≤0.0002%; Ca: ≤0.001%; Ca: ≤0.005%; Cu: ≤0.0003%; Fe: ≤0.0005%; K: ≤0.005%; Mg: ≤0.0005%; Mg: ≤0.005%; N: ≤0.001%; Pb: ≤0.0005%; heavy metals (as Pb): ≤0.0005%
• UV absorption: λ: 254 nm A_max: ≤0.02; λ: 280 nm A_max: ≤0.01; λ: 350 nm A_max: ≤0.01
• storage temp.: 2-30°C
• SMILES string: O.O.O.[Na+].CC([O-])=O
• InChI: 1S/C2H4O2.Na.3H2O/c1-2(3)4;;;;/h1H3,(H,3,4);;3*1H2/q;+1;;;/p-1
• InChI key: AYRVGWHSXIMRAB-UHFFFAOYSA-M

Description

Application

• Direct Affinity Ligand Immobilization onto Bare Iron Oxide Nanoparticles Enables Efficient Magnetic Separation of Antibodies: Highlights the role of sodium acetate trihydrate in bioengineering, particularly in the enhancement of magnetic nanoparticle performance for bioseparation applications (Zimmermann I, Berensmeier S, 2024).


• Physicochemical and antioxidant properties of pectin fractions extracted from lemon (Citrus Eureka) peels: Details the use of sodium acetate trihydrate in the extraction and analysis of bioactive compounds, supporting its critical role in food science and nutraceutical applications (Su Z, Li G, 2024).

Other Notes

Enzyme substrate for acetate kinase (EC 2.7.2.1)

Linkage

Replaces: SX0255; SX0255-1; SX0255-3; SX0255-20

Analysis Note

Assay (perchloric acid titration): 99.0 - 101.0 %
Assay (perchloric acid titration, calculated on dried substance): 99.0 - 101.0 %
Identity: passes test
Appearance of solution: passes test
Insoluble matter: ≤ 0.005 %
pH-value (5 %; water): 7.5 - 9.0
Chloride (Cl): ≤ 0.0005 %
Phosphate (PO₄): ≤ 0.0002 %
Sulfate (SO₄): ≤ 0.002 %
Total nitrogen (N): ≤ 0.001 %
Heavy metals (as Pb): ≤ 0.0005 %
Al (Aluminium): ≤ 0.0005 %
As (Arsenic): ≤ 0.0002 %
Ca (Calcium): ≤ 0.001 %
Cu (Copper): ≤ 0.0003 %
Fe (Iron): ≤ 0.0005 %
K (Potassium): ≤ 0.005 %
Mg (Magnesium): ≤ 0.0005 %
Pb (Lead): ≤ 0.0005 %
Calcium and Magnesium (as Ca): ≤ 0.005 %
Substances reducing permanganate: passes test
Reducing substances: ≤ 0.005 %
Loss on drying (130 °C): 39.0 - 40.5 %
UV absorption (254 nm; 1 mol/l; 1 cm; water): ≤ 0.02
UV absorption (280 nm; 1 mol/l; 1 cm; water): ≤ 0.01
UV absorption (350 nm; 1 mol/l; 1 cm; water): ≤ 0.01
Corresponds to ACS,ISO,Reag. Ph Eur

Legal Information

EMSURE is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable