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860478P

Avanti

cis-4-methylsphingosine

Avanti Research - A Croda Brand

Synonym(s):

5-Nonadecene-1,4-diol, 3-amino-5-methyl-, (3R,4S,5Z)-

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About This Item

Empirical Formula (Hill Notation):
C19H39NO2
CAS Number:
Molecular Weight:
313.52
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 5 mg (860478P-5mg)

manufacturer/tradename

Avanti Research - A Croda Brand

lipid type

sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

CCCCCCCCCCCCC/C=C(C)\[C@@H](O)[C@@H](N)CO

General description

cis-4-methylsphingosine (cis-4M-Sph) is a methyl-branched sphingosine analog.

Biochem/physiol Actions

cis-4-methylsphingosine (cis-4M-Sph) modulates sphingosine 1 phosphate (S1P) receptor through its metabolite cis-4-methylsphingosine-1-phosphate (cis-4M-S1P). This leads to S1P receptor internalization and desensitization. cis-4M-Sph shows an inhibitory effect on serine palmitoyltransferase activity.

Packaging

5 mL Amber Glass Screw Cap Vial (860478P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3


Certificates of Analysis (COA)

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Wenzheng Xia et al.
Molecular medicine reports, 16(5), 7039-7047 (2017-09-14)
Mesenchymal stem cell (MSC)‑based therapies have demonstrated efficacy in animal models of cardiovascular diseases. However, MSCs decrease in quantity and quality with age, which reduces their capacity for damage repair. Long noncoding (lnc) RNAs regulate gene transcription and the fate

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