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840503C

Avanti

18:0-18:1 PG

1-stearoyl-2-oleoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt), chloroform

Synonym(s):

1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1′racglycerol) (sodium salt); SOPG; PG(18:0/18:1(9Z)); 110652

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About This Item

Empirical Formula (Hill Notation):
C42H80O10PNa
CAS Number:
322647-48-3
Molecular Weight:
799.04
UNSPSC Code:
51191904
NACRES:
NA.25

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (840503C-25mg)
pkg of 2 × 4 mL (840503C-200mg)

manufacturer/tradename

Avanti Polar Lipids 840503C

concentration

10 mg/mL (840503C-25mg)
25 mg/mL (840503C-200mg)

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

InChI

1S/C42H81O10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-41(45)49-37-40(38-51-53(47,48)50-36-39(44)35-43)52-42(46)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h18,20,39-40,43-44H,3-17,19,21-38H2,1-2H3,(H,47,48);/q;+1/p-1/b20-18-;/t39?,40-;/m1./s1

InChI key

AZUBILBUHSANJX-VDVGXYCESA-M

General description

18:0-18:1 PG (SOPG/1-stearoyl-2-oleoyl-sn-glycero-3-phospho-(1′-rac-glycerol)) is a hydrogenated phospholipid. It has two additional methylene groups in its saturated sn-1 chain. The thylakoid membranes of higher plants and cyanobacteria has phosphatidylglycerol (PG).

Application

18:0-18:1 PG (1-stearoyl-2-oleoyl-sn-glycero-3-phospho-(1′-rac-glycerol)) may be used:
  • as a component in biocompatible phospholipid bilayer to coat the gold nanoparticles (GNPs) surface
  • in liposomes preparation
  • in the formation of lipid monolayer

Biochem/physiol Actions

Phosphatidylglycerol (PG) helps to maintain the stability of photosystem I and II protein complexes. It is involved in bacterial defense mechanisms.

Packaging

5 mL Clear Glass Sealed Ampule (840503C-200mg)
5 mL Clear Glass Sealed Ampule (840503C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Jianjun Pan et al.
Biochimica et biophysica acta, 1818(9), 2135-2148 (2012-05-16)
We have determined the molecular structures of commonly used phosphatidylglycerols (PGs) in the commonly accepted biologically relevant fluid phase. This was done by simultaneously analyzing small angle neutron and X-ray scattering data, with the constraint of measured lipid volumes. We
J P Michel et al.
Langmuir : the ACS journal of surfaces and colloids, 33(41), 11028-11039 (2017-09-19)
The outer membrane (OM) of Gram-negative bacteria is a complex and asymmetric bilayer that antimicrobial peptides must disrupt in order to provoke the cell lysis. The inner and external leaflets of the OM are mainly composed of phospholipids (PL), and
Joury S van 't Klooster et al.
eLife, 9 (2020-04-18)
Yeast tolerates a low pH and high solvent concentrations. The permeability of the plasma membrane (PM) for small molecules is low and lateral diffusion of proteins is slow. These findings suggest a high degree of lipid order, which raises the
Ildiko Van Rhijn et al.
Proceedings of the National Academy of Sciences of the United States of America, 113(2), 380-385 (2015-12-02)
In contrast with the common detection of T cells that recognize MHC, CD1a, CD1c, or CD1d proteins, CD1b autoreactive T cells have been difficult to isolate in humans. Here we report the development of polyvalent complexes of CD1b proteins and
Annemieke de Jong et al.
Nature immunology, 15(2), 177-185 (2013-12-24)
T cells autoreactive to the antigen-presenting molecule CD1a are common in human blood and skin, but the search for natural autoantigens has been confounded by background T cell responses to CD1 proteins and self lipids. After capturing CD1a-lipid complexes, we

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