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93578

Sigma-Aldrich

Poly(L-lactide)

viscosity ~1.0 dL/g, 0.1 % (w/v) in chloroform(25 °C)

Synonym(s):

L-Lactide polymer, PLA, Poly(L-Lactic acid)

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About This Item

Linear Formula:
CH3O(C6H8O4)nH
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.21

description

ester terminated

Quality Level

form

solid

mol wt

Mn 59,000
Mw 101,000

degradation timeframe

>3 years

impurities

<0.5% water

viscosity

~1.0 dL/g, 0.1 % (w/v) in chloroform(25 °C)

Mw/Mn

<1.8

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Application

medical device

Other Notes

end group: dodecyl ester

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Germano Piccirillo et al.
Acta biomaterialia, 52, 187-196 (2016-11-07)
Actinic Keratosis' (AKs) are small skin lesions that are related to a prolonged sun-damage, which can develop into invasive squamous cell carcinoma (SCC) when left untreated. Effective, specific and well tolerable therapies to cure AKs are still of great interest.
Joon H Eoh et al.
Acta biomaterialia, 52, 49-59 (2017-02-07)
Obtaining vascular smooth muscle tissue with mature, functional elastic fibers is a key obstacle in tissue-engineered blood vessels. Poor elastin secretion and organization leads to a loss of specialization in contractile smooth muscle cells, resulting in over proliferation and graft
Svenja Hinderer et al.
Scientific reports, 8(1), 110-110 (2018-01-10)
Decorin (DCN) is an important small leucine-rich proteoglycan present in the extracellular matrix (ECM) of many organs and tissues. Endothelial progenitor cells (EPCs) are able to interact with the surrounding ECM and bind to molecules such as DCN. Here, we
Svenja Hinderer et al.
Biomedical materials (Bristol, England), 10(3), 034102-034102 (2015-03-19)
Elastic fibers are essential for the proper function of organs including cardiovascular tissues such as heart valves and blood vessels. Although (tropo)elastin production in a tissue-engineered construct has previously been described, the assembly to functional elastic fibers in vitro using

Articles

Interest in utilizing biodegradable polymers for biomedical applications has grown since the 1960s.

Aliphatic polyesters such as polylactide, poly(lactide-co-glycolide) and polycaprolactone, as well as their copolymers, represent a diverse family of synthetic biodegradable polymers that have been widely explored for medical uses and are commercially available.

Aliphatic polyesters such as polylactide, poly(lactide-co-glycolide) and polycaprolactone, as well as their copolymers, represent a diverse family of synthetic biodegradable polymers that have been widely explored for medical uses and are commercially available.

In the past two decades, tissue engineering and regenerative medicine have become important interdisciplinary fields that span biology, chemistry, engineering, and medicine.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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