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922668

Sigma-Aldrich

Dichloromeldrum′s acid

≥95%

Synonym(s):

5,5-Dichloro-2,2-dimethyl-1,3-dioxane-4,6-dione, DiCMA, Lennox-Heard chloroacetylation reagent

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About This Item

Empirical Formula (Hill Notation):
C6H6Cl2O4
CAS Number:
Molecular Weight:
213.02
UNSPSC Code:
12352106
NACRES:
NA.22

Quality Level

Assay

≥95%

form

chunks

mp

51-54 °C

functional group

chloro
ester
ketal

Application

Lennox-Heard reagent (also known as dichloromeldrum′s acid, or DiCMA) is a stable, shelf-stable reagent for the conversion of alkyl and aryl amines to dichloroacetamides. This reagent is atom economical and the byproducts of acetone and CO2 are easily removed, and provides a greener, practical method of installing these medicinally relevant motifs onto a variety of compounds in high yield.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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