919012
PEI Prime™ linear polyethylenimine
suitable for gene delivery
Synonym(s):
PEI
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About This Item
Linear Formula:
(C2H5N . HCl)n
CAS Number:
MDL number:
UNSPSC Code:
12162002
NACRES:
NA.23
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Application
PEI Prime™ is a cationic polymer designed for high-yield, reproducible and scalable drug and gene delivery. As a gene carrier, PEI forms a complex with nucleic acids via electrostatic self-assembly between the negatively charged nucleic acid phosphate groups and positively charged PEI amine groups. Due to this interaction, PEI has been extensively explored as a gene carrier and is one of the most effective synthetic polymers for the delivery of nucleic acids into cells through endocytosis.
PEI Prime™ uses an optimized form of PEI to reduce performance variance and speed process development time. Each batch of PEI Prime™ undergoes triplicate, quantitative performance testing using an SEAP reporter assay. PEI Prime™ is an excellent choice to produce any biologic cost-effectively, including recombinant proteins, antibodies, and viruses.
PEI Prime™ uses an optimized form of PEI to reduce performance variance and speed process development time. Each batch of PEI Prime™ undergoes triplicate, quantitative performance testing using an SEAP reporter assay. PEI Prime™ is an excellent choice to produce any biologic cost-effectively, including recombinant proteins, antibodies, and viruses.
Legal Information
PEI Prime is a trademark of Serochem LLC
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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S M Zou et al.
The journal of gene medicine, 2(2), 128-134 (2000-05-16)
Several nonviral vectors including linear polyethylenimine (L-PEI) confer a pronounced lung tropism to plasmid DNA when injected into the mouse tail vein in a nonionic solution. and results We have optimized this route by injecting 50 microg DNA with excess
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