905240

(R,R,R)-SPIRAP

≥95%

• Synonym(s): ((1R,3R,3′R)-3,3′-diethyl-3H,3′H-1,1′-spirobi[isobenzofuran]-7,7′-diyl)bis(diphenylphosphane), (R)-CrabPhos
• Empirical Formula (Hill Notation): C₄₃H₃₈O₂P₂
• Molecular Weight: 648.71

Properties

• Assay: ≥95%
• form: powder or crystals
• reaction suitability: reagent type: ligand; reaction type: Asymmetric synthesis
• mp: 226-228 °C
• SMILES string: CC[C@@H](O1)C2=C([C@@]1(O[C@@H]3CC)C4=C3C=CC=C4P(C5=CC=CC=C5)C6=CC=CC=C6)C(P(C7=CC=CC=C7)C8=CC=CC=C8)=CC=C2

Description

Application

(R,R,R)-SPIRAP is a chiral C₂-symmetric spiroketal-containing ligand developed in the Nagorny lab for asymmetric catalysis. It can be used in variety of stereoselective transformations, including: Ir-catalyzed hydroarylation, Pd-catalyzed allylic alkylation, Pd-catalyzed Heck couplings, and Rh-catalyzed hydrogenation.

Product can be used with our benchtop hydrogen generator, H-Genie Lite (Z744083)

Other Notes

Design, Synthesis, and Application of Chiral C₂-Symmetric Spiroketal-Containing Ligands in Transition-Metal Catalysis

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable