391913

(R)-(+)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid

98%

• Synonym(s): (2R)-3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-carboxylic acid, (R)-Trolox
• Empirical Formula (Hill Notation): C₁₄H₁₈O₄
• CAS Number: 53101-49-8
• Molecular Weight: 250.29
• MDL number: MFCD00180755
• UNSPSC Code: 12352005
• PubChem Substance ID: 24864410
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 98%
• form: solid
• optical activity: [α]27/D +65°, c = 1.2 in ethanol
• mp: 162 °C (dec.) (lit.)
• functional group: carboxylic acid
• SMILES string: Cc1c(C)c2O[C@](C)(CCc2c(C)c1O)C(O)=O
• InChI: 1S/C14H18O4/c1-7-8(2)12-10(9(3)11(7)15)5-6-14(4,18-12)13(16)17/h15H,5-6H2,1-4H3,(H,16,17)/t14-/m1/s1
• InChI key: GLEVLJDDWXEYCO-CQSZACIVSA-N

Description

General description

(R)-(+)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid, a vitamin E analog, is a mushroom tyrosinase inhibitor.

Application

(R)-(+)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid may be used to incorporate antioxidant property while designing anti-stress agents based on γ-aminobutyric acid (GABA).

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves