377074

Pentafluorophenyl trifluoroacetate

98%, for peptide synthesis

• Synonym(s): Trifluoroacetic acid pentafluorophenyl ester
• Linear Formula: CF₃CO₂C₆F₅
• CAS Number: 14533-84-7
• Molecular Weight: 280.07
• Beilstein: 2003848
• MDL number: MFCD00134438
• UNSPSC Code: 12352101
• PubChem Substance ID: 24863490
• NACRES: NA.22

Properties

• Product Name: Pentafluorophenyl trifluoroacetate, 98%
• Quality Level: 200
• Assay: 98%
• form: liquid
• refractive index: n20/D 1.368 (lit.)
• bp: 122-123 °C (lit.)
• density: 1.63 g/mL at 25 °C (lit.)
• application(s): peptide synthesis
• functional group: ester; fluoro
• SMILES string: Fc1c(F)c(F)c(OC(=O)C(F)(F)F)c(F)c1F
• InChI: 1S/C8F8O2/c9-1-2(10)4(12)6(5(13)3(1)11)18-7(17)8(14,15)16
• InChI key: VCQURUZYYSOUHP-UHFFFAOYSA-N

Description

Application

Pentafluorophenyl trifluoroacetate can be used:

• In the esterification of 2′-carboxyrhodamine dye to form pentafluorophenyl ester as a single isomer.
• As an acylating agent and a coupling agent for the peptide-type coupling of N-substituted glycine oligomers.
• In the synthesis of pentafluorophenyl thiophene-3-acetate (PFPTA) by reacting with 3-thiopheneacetic acid.

Other Notes

may contain a small amount of pentafluorophenol

Safety Information

• Pictograms: GHS02,GHS07
• Signal Word: Warning
• Hazard Statements: H226,H315,H319,H335
• Precautionary Statements: P210 - P233 - P240 - P241 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point(F): 125.6 °F - closed cup
• Flash Point(C): 52 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves