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112933

Sigma-Aldrich

Acetanilide

99%

Synonym(s):

N-Phenylacetamide

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About This Item

Linear Formula:
CH3CONHC6H5
CAS Number:
103-84-4
Molecular Weight:
135.16
Beilstein:
606468
EC Number:
203-150-7
MDL number:
MFCD00008674
UNSPSC Code:
12352100
eCl@ss:
39031308
PubChem Substance ID:
57646910
NACRES:
NA.22

vapor density

4.65 (vs air)

Quality Level

200

vapor pressure

1 mmHg ( 114 °C)

Assay

99%

form

solid

autoignition temp.

1004 °F

bp

304 °C (lit.)

mp

113-115 °C (lit.)

SMILES string

CC(=O)Nc1ccccc1

InChI

1S/C8H9NO/c1-7(10)9-8-5-3-2-4-6-8/h2-6H,1H3,(H,9,10)

InChI key

FZERHIULMFGESH-UHFFFAOYSA-N

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General description

Acetanilide undergoes palladium-catalyzed cross-coupling reaction to form ortho-acylacetanilide.

Application

Acetanilide is used as a EOF (electroosmotic flow) marker in the studies of affinity capillary electrophoresis for drug–protein binding.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

321.8 °F - closed cup

Flash Point(C)

161 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Sigma-Aldrich

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Sigma-Aldrich

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Acetamide

Deia El-Hady et al.
Journal of pharmaceutical and biomedical analysis, 52(2), 232-241 (2010-01-19)
In order to achieve excellent precision in the estimation of binding constants by affinity capillary electrophoresis (ACE), electroosmotic flow (EOF) stability is the key parameter, especially when using proteins in binding assays. Appropriate rinsing protocols are mandatory. In our study
Zetty Azalea Sutirman et al.
International journal of biological macromolecules, 133, 1260-1267 (2019-05-03)
Grafting of crosslinked chitosan with monomer, N-vinyl-2-pyrrolidone, has been carried out to investigate its adsorption capacity toward Orange G (OG) from aqueous solutions. The adsorption performance of modified chitosan (cts(x)-g-PNVP) was examined and compared with that of the unmodified chitosan.
Yinuo Wu et al.
Chemical communications (Cambridge, England), 49(7), 689-691 (2012-12-12)
A palladium-catalyzed cascade cross-coupling of acetanilide and toluene for the synthesis of ortho-acylacetanilide is described. Toluene derivatives can act as effective acyl precursors (upon sp(3)-C-H bond oxidation by a Pd/TBHP system) in the oxidative coupling between two C-H bonds. This
Khaled M Mohamed et al.
Biomedical chromatography : BMC, 30(12), 1922-1927 (2016-05-25)
Cases of poisoning by p-phenylenediamine (PPD) are detected sporadically. Recently an article on the development and validation of an LC-MS/MS method for the detection of PPD and its metabolites, N-acetyl-p-phenylenediamine (MAPPD) and N,N-diacetyl-p-phenylenediamine (DAPPD) in blood was published. In the
Weiwei Qin et al.
Journal of chromatography. A, 1432, 84-91 (2016-01-21)
Metal-organic framework (MOF) MIL-100(Fe) with well-defined thickness was homogenously coated onto the outer surface of magnetic microparticles via a liquid-phase epitaxy method. The as-synthesized MIL-100(Fe) was used as stationary phase for high-performance liquid chromatography (HPLC) and separations of two groups
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