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Z0292

Sigma-Aldrich

α-Zearalanol

~98% (HPLC), powder, mycotoxin

Sinónimos:

2,4-Dihydroxy-6-(6α,10-dihydroxyundecyl)benzoic acid μ-lactone

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About This Item

Fórmula empírica (notación de Hill):
C18H26O5
Número de CAS:
26538-44-3
Peso molecular:
322.40
EC Number:
247-769-0
MDL number:
MFCD00083519
UNSPSC Code:
12352200
PubChem Substance ID:
24902163
NACRES:
NA.77

Nombre del producto

α-Zearalanol, ~98% (HPLC)

biological source

synthetic (organic)

Quality Level

200

sterility

non-sterile

assay

~98% (HPLC)

form

powder

drug control

regulated under CDSA - not available from Sigma-Aldrich Canada

technique(s)

UHPLC: suitable

solubility

methanol: 1.96-2.04 mg/mL, clear, colorless to faintly yellow

shipped in

ambient

storage temp.

−20°C

SMILES string

C[C@H]1CCC[C@H](O)CCCCCc2cc(O)cc(O)c2C(=O)O1

InChI

1S/C18H26O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h10-12,14,19-21H,2-9H2,1H3/t12-,14+/m0/s1

InChI key

DWTTZBARDOXEAM-GXTWGEPZSA-N

pictograms

Health hazardCorrosion
GHS08,GHS05

signalword

Danger

Hazard Classifications

Repr. 2 - Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificados de análisis (COA)

Lot/Batch Number
039M4042V
14180802
038M4025V
087M4127V
14170218

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C Mastri et al.
Journal of steroid biochemistry, 23(3), 279-289 (1985-09-01)
It is now well established that the mycotoxin zearalenone and some of its derivatives possess oestrogenic activity. In the present study, the binding characteristics of [3H]zearalanol (P-1496) to different classes of sites including [1] the oestrogen receptor, [2] the higher
Angela Filannino et al.
Reproductive biology and endocrinology : RB&E, 9, 134-134 (2011-10-06)
The aim of this study was to investigate the in vitro effects of the Fusarium fungus-derived mycotoxin, zearalenone and its derivatives alpha-zearalenol and beta-zearalenol on motility parameters and the acrosome reaction of stallion sperm. Since the toxic effects of zearalenone
Shen Qu et al.
Environmental science & technology, 46(24), 13202-13211 (2012-11-21)
Trenbolone acetate, melengestrol acetate, and zeranol are synthetic hormones extensively used as growth promoters in animal agriculture, yet despite occurrence in water and soil little is known about their environmental fate. Here, we establish the time scales and mechanisms by
A Pazaiti et al.
International journal of clinical practice, 66(1), 28-36 (2011-12-08)
Zearalenone (ZEN) is a non-steroidal mycoestrogen that widely contaminates agricultural products. ZEN and its derivatives share similar molecular mechanisms and activity with estrogens and interact with ERα and ERβ leading to changes in the reproductive system in both animals and
Stefanie C Fleck et al.
Toxicology letters, 210(1), 9-14 (2012-01-31)
α-Zearalanol (α-ZAL, zeranol) is a highly estrogenic macrocyclic β-resorcylic acid lactone, which is used as a growth promotor for cattle in various countries. We have recently reported that α-ZAL and its major metabolite zearalanone (ZAN) are hydroxylated at the aromatic
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