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T3915

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Transferrin-biotin labeled human

lyophilized powder containing sodium citrate

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About This Item

Número de CAS:
EC Number:
MDL number:
UNSPSC Code:
12352202
eCl@ss:
34058011
NACRES:
NA.83

biological source

human

Quality Level

form

powder

composition

Protein, ~90% biuret

extent of labeling

4-8 mol d-biotin per mol transferrin

technique(s)

cell culture | mammalian: suitable

UniProt accession no.

storage temp.

−20°C

Gene Information

human ... TF(7018)

Application

Biotin-labeled transferrin is commonly used to monitor transferrin uptake by cells in vitro through addition to the cell culture medium.

Physical form

Lyophilized powder containing sodium citrate

Preparation Note

Prepared from human holo-transferrin, coupled to biotin by an amide bond through an aminocaproyl spacer.

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3


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Francesca Guerrieri et al.
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Dominik P Buser et al.
EBioMedicine, 46, 32-41 (2019-07-25)
Gliomas are the most frequent and aggressive malignancies of the central nervous system. Decades of molecular analyses have demonstrated that gliomas accumulate genetic alterations that culminate in enhanced activity of receptor tyrosine kinases and downstream mediators. While the genetic alterations
Henri-François Renard et al.
Nature communications, 11(1), 1457-1457 (2020-03-21)
While several clathrin-independent endocytic processes have been described so far, their biological relevance often remains elusive, especially in pathophysiological contexts such as cancer. In this study, we find that the tumor marker CD166/ALCAM (Activated Leukocyte Cell Adhesion Molecule) is a
Xiaonan Dong et al.
Nature, 589(7842), 456-461 (2020-12-18)
Autophagy, a process of degradation that occurs via the lysosomal pathway, has an essential role in multiple aspects of immunity, including immune system development, regulation of innate and adaptive immune and inflammatory responses, selective degradation of intracellular microorganisms, and host

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