SRP6367

KLRK1 human

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

• Sinónimos: CD314, D12S2489E, KLR, NKG2-D, NKG2-D type II integral membrane protein, NKG2D
• UNSPSC Code: 12352200
• NACRES: NA.32

Propiedades

• biological source: human
• recombinant: expressed in E. coli
• assay: ≥90% (SDS-PAGE)
• form: liquid
• mol wt: 19.2 kDa (168 aa, 73-216 aa + His Tag)
• packaging: pkg of 100 μg
• concentration: 0.5 mg/mL
• UniProt accession no.: P26718
• shipped in: dry ice
• storage temp.: −70°C
• Gene Information: human ... KLRK1(22914)

Descripción

General description

KLRK1 is an activating receptor that has recently generated considerable interest. The most intriguing of these are a pair of closely related proteins called MICA and MICB. These are cell-surface molecules distantly related to MHC class I proteins, and the genes possess elements of heat shock promoters. MICA and MICB, therefore, are expressed during cell stress and are up-regulated in tumor cells and during viral infections. This receptor-ligand combination may play a critical role in the immune response to a variety of pathologies. Recombinant human KLRK1 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Physical form

0.5 mg/mL in 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea and 10% glycerol.

Información de seguridad

• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable