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SRP4039

Sigma-Aldrich

Fgf-2 from rat

recombinant, expressed in E. coli, ≥97% (SDS-PAGE), ≥97% (HPLC)

Sinónimos:

FGB-b, FGF-2, Fibroblast Growth Factor-basic, HBGF-2, Prostatropin

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.32

biological source

rat

recombinant

expressed in E. coli

assay

≥97% (HPLC)
≥97% (SDS-PAGE)

form

lyophilized

potency

<0.2 ng/mL

mol wt

~16.3 kDa

packaging

pkg of 50 μg

storage condition

avoid repeated freeze/thaw cycles

impurities

endotoxin, tested

NCBI accession no.

P13109

UniProt accession no.

P13109

shipped in

wet ice

storage temp.

−20°C

Gene Information

rat ... Fgf2(54250)

General description

Fibroblast growth factor-2 (FGF-2) is a basic heparin binding growth factor and a profibrotic factor. The recombinant mouse FGF-2 is a single, non-glycosylated chain containing 145 amino acids and having a molecular weight of 16.3kDa.

Biochem/physiol Actions

Fibroblast growth factor-2 (FGF-2) stimulates the proliferation of a wide variety of cells including mesenchymal, neuroectodermal and endothelial cells.

Physical form

Lyophilized from 1 mg/ml solution after extensive dialysis against 20 mM phosphate buffer, pH 7.4 and 130 mM NaCl.

Reconstitution

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
Reconstitute in sterile water to 0.1–1 mg/mL.

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Apocynin Attenuates Cardiac Injury in Type 4 Cardiorenal Syndrome via Suppressing Cardiac Fibroblast Growth Factor-2 With Oxidative Stress Inhibition.
Liu Y
Journal of the American Heart Association, 4(7), e001598-e001598 (2015)
FGF-18, a novel member of the fibroblast growth factor family, stimulates hepatic and intestinal proliferation.
Hu MC
Molecular and Cellular Biology, 18(10), 6063-6074 (1998)
Zsuzsanna Táncos et al.
Gene, 566(2), 148-157 (2015-04-22)
While the rabbit (Oryctolagus cuniculus) is an important research model for aspects of human development and disease that cannot be studied in rodents, the lack of data on the genetic regulation of rabbit preimplantation development is a limitation. To assist
Senthil S Saravanamuthu et al.
Developmental biology, 332(1), 166-176 (2009-06-02)
Previous studies of the developing lens have shown that Notch signaling regulates differentiation of lens fiber cells by maintaining a proliferating precursor pool in the anterior epithelium. However, whether Notch signaling is further required after the onset of fiber cell
Yayoi Yoshimura et al.
PloS one, 10(6), e0128288-e0128288 (2015-06-04)
Glioblastoma multiforme (GBM) is associated with high mortality due to infiltrative growth and recurrence. Median survival of the patients is less than 15 months, increasing requirements for new therapies. We found that both arsenic trioxide and 10058F4, an inhibitor of
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