SML2532

Jedi2

≥98% (HPLC)

• Sinónimos: 2-Methyl-5-(2-thienyl)-3-furancarboxylic acid
• Fórmula empírica (notación de Hill): C₁₀H₈O₃S
• Número de CAS: 651005-90-2
• Peso molecular: 208.23
• MDL number: MFCD01569561
• UNSPSC Code: 12352200
• NACRES: NA.77

Propiedades

• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: [s]1c(ccc1)c2[o]c(c(c2)C(=O)O)C
• InChI: 1S/C10H8O3S/c1-6-7(10(11)12)5-8(13-6)9-3-2-4-14-9/h2-5H,1H3,(H,11,12)
• InChI key: YXDCRSXNEOKXDE-UHFFFAOYSA-N

Descripción

Biochem/physiol Actions

Jedi2 is an activator of the mechanosensitive Piezo1 channel that binds at a different place from Yoda1. It exhibits long-range allosteric gating, activating Piezo1 through the extracellular side of its peripheral blade-like structure rather than the C-terminal extracellular domain of the pore.

Piezo1 channel activator

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H302,H315,H317,H319
• pcodes: P261 - P264 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable