SML1606

Oseltamivir phosphate

≥98% (HPLC)

• Sinónimos: GS4104, (3R,4R,5S)-4-Acetamido-5-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylic acid ethyl ester phosphate salt
• Fórmula empírica (notación de Hill): C₁₆H₂₈N₂O₄ ·H₃PO₄
• Número de CAS: 204255-11-8
• Peso molecular: 410.40
• MDL number: MFCD08059548
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825492
• NACRES: NA.77

Propiedades

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• optical activity: [α]/D -26 to -36°, c = 1 in H₂O
• color: white to beige
• solubility: H₂O: 30 mg/mL, clear
• storage temp.: −20°C
• SMILES string: OP(O)(O)=O.CCOC(=O)C1=C[C@@H](OC(CC)CC)[C@H](NC(C)=O)[C@@H](N)C1
• InChI: 1S/C16H28N2O4.H3O4P/c1-5-12(6-2)22-14-9-11(16(20)21-7-3)8-13(17)15(14)18-10(4)19;1-5(2,3)4/h9,12-15H,5-8,17H2,1-4H3,(H,18,19);(H3,1,2,3,4)/t13-,14+,15+;/m0./s1
• InChI key: PGZUMBJQJWIWGJ-ONAKXNSWSA-N

Descripción

Biochem/physiol Actions

Oseltamivir phosphate is an influenza viral neuraminidase inhibitor. Oseltamivir phosphate, an antiviral, is used clinically to treat influenza A and influenza B, and to prevent flu after exposure. Oseltamivir phosphate is hydrolyzed in the liver to its active form, oseltamivir carboxylate, which is an inhibitor of influenza viral neuraminidases essential for viral replication. Oseltamivir has a broad spectrum of activity against a range of influenza A and B subtypes with IC₅₀ values for neuraminidases measured from less than 1 nM to approximately 30 nM, depending on the virus subtype.

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H317,H319,H412
• pcodes: P261 - P264 - P273 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Aquatic Chronic 3 - Eye Irrit. 2 - Skin Sens. 1
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable