SML1405

MS37452

≥98% (HPLC)

• Sinónimos: 1-(2,3-Dimethoxybenzoyl)-4-[(3-methylphenoxy)acetyl]-piperazine (9CI), 1-[4-(2,3-Dimethoxybenzoyl)-1-piperazinyl]-2-(3-methylphenoxy)-ethanonemethylphenoxy)acetyl]-piperazine (9CI)
• Fórmula empírica (notación de Hill): C₂₂H₂₆N₂O₅
• Número de CAS: 423748-02-1
• Peso molecular: 398.45
• MDL number: MFCD03134667
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825852
• NACRES: NA.77

Propiedades

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to beige
• solubility: DMSO: 20 mg/mL, clear
• shipped in: wet ice
• storage temp.: −20°C
• SMILES string: O=C(COC1=CC(C)=CC=C1)N2CCN(C(C3=CC=CC(OC)=C3OC)=O)CC2
• InChI: 1S/C22H26N2O5/c1-16-6-4-7-17(14-16)29-15-20(25)23-10-12-24(13-11-23)22(26)18-8-5-9-19(27-2)21(18)28-3/h4-9,14H,10-13,15H2,1-3H3
• InChI key: LUMCNRKHZRYQOV-UHFFFAOYSA-N

Descripción

Biochem/physiol Actions

MS37452 is a selective Chromobox homolog 7 (CBX7) modulator that disrupts CBX7ChD binding to H3K27me3. MS37452 inhibits CBX7 binding to INK4/ARF gene locus, and induces decline of p14/ARF and p16/INK4a in human PC3 cells.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable