SML1220

Doripenem hydrate

≥98% (HPLC)

• Sinónimos: (4R,5S,6S)-3-[[(3S,5S)-5-[[(Aminosulfonyl)amino]methyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid hydrate
• Fórmula empírica (notación de Hill): C₁₅H₂₄N₄O₆S₂ · H₂O
• Número de CAS: 364622-82-2
• Peso molecular: 438.52
• MDL number: MFCD09749887
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825727
• NACRES: NA.77

Propiedades

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: H₂O: 5 mg/mL, clear (warmed)
• storage temp.: 2-8°C
• InChI: 1S/C15H24N4O6S2.H2O/c1-6-11-10(7(2)20)14(21)19(11)12(15(22)23)13(6)26-9-3-8(17-5-9)4-18-27(16,24)25;/h6-11,17-18,20H,3-5H2,1-2H3,(H,22,23)(H2,16,24,25);1H2/t6-,7-,8+,9+,10-,11-;/m1./s1
• InChI key: NTUBEBXBDGKBTJ-WGLOMNHJSA-N

Descripción

Biochem/physiol Actions

Doripenem hydrate is used to treat complicated urinary infection including Pyelonephritis caused by E.coli. Doripenem hydrate is promoted in the United States as DORIBAX^®. This drug is synthesized from p-nitrobenzyl-protected enolphosphate 2b and N-(p-nitrobenzyloxycarbonyl)-protected aminomethylpyrrolidine.

Doripenem is an ultra-broad spectrum carbopenem antibiotic. Doripenem is active against both gram-positive and gram-negative bacteria.

Legal Information

DORIBAX is a registered trademark of Shionogi Inc.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable