SML0818

A-841720

≥98% (HPLC)

• Sinónimos: 9-(Dimethylamino)-3-(hexahydro-1H-azepin-1-yl)-pyrido[3′,2′:4,5]thieno[3,2-d]pyrimidin-4(3H)-one
• Fórmula empírica (notación de Hill): C₁₇H₂₁N₅OS
• Número de CAS: 869802-58-4
• Peso molecular: 343.45
• UNSPSC Code: 12352202
• NACRES: NA.77

Propiedades

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 15 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: [s]1c2nccc(c2c3nc[n]([c](c31)=O)N4CCCCCC4)N(C)C
• InChI: 1S/C17H21N5OS/c1-20(2)12-7-8-18-16-13(12)14-15(24-16)17(23)22(11-19-14)21-9-5-3-4-6-10-21/h7-8,11H,3-6,9-10H2,1-2H3
• InChI key: GYWGXEGOXODOQU-UHFFFAOYSA-N

Descripción

Biochem/physiol Actions

A-841720 is a potent, selective, non-competitive mGluR1 antagonist that displays greater than 30-fold selectivity over another Group I metabotopic glutamate receptor, mGluR5. The compound has potent analgesic properties, and can also diminish motor and cognitive activity.

Features and Benefits

This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable