SAB5801061

Rabbit Anti-Alpaca IgG2c Alpaca Heavy chain only Antibody

recombinant Alpaca(VHH) Nano antibody

• Sinónimos: Recombinant Alpaca single variable domain secondary Nanobody
• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• biological source: alpaca
• recombinant: expressed in HEK 293 cells (Human cell line)
• conjugate: unconjugated
• antibody form: affinity purified immunoglobulin
• antibody product type: secondary antibodies
• clone: recombinant monoclonal
• form: lyophilized solid
• mol wt: 100 kDa
• species reactivity: Alpaca, (alpaca)
• technique(s): ELISA: 1:4000-1:10000; western blot: 1:4000-1:10000
• size: 0.1 mL
• color: colorless
• isotype: VHH
• shipped in: wet ice
• storage temp.: 2-8°C

Descripción

General description

Rabbit Anti-Alpaca IgG2c Alpaca Heavy chain only Antibody is designed to specifically detect Alpaca IgG2c. It is a monovalent, recombinant single chain antibody fragment fused to rabbit IgG Fc. Based on immunoelectrophoresis and/or ELISA, Rabbit Anti-Alpaca IgG2c Alpaca Heavy chain only Antibody reacts with Alpaca IgG2c selectively, no cross-reactivity with Alpaca IgG1/2b.

The biological family Camelidae comprises camels (one-humped Camelus dromedarius and two-humped Camelus bactrianus), llama (Lama glama and Lama guanicoe), and vicugna (Vicugna vicugna and Vicugna pacos). Camelidae contain two kinds of IgG in serum: conventional antibodies (IgG1) containing two light chains and two heavy chains (composed of the VH, CH1, hinge, and CH2 and CH3 domains) and two types of homodimeric heavy-chain antibodies (HCAbs), IgG2 and IgG3, which comprise only H chains: each H chain contains a VHH, hinge, and CH2 and CH3 domains. The smallest intact functional antigen-binding fragment of HCAbs is the single-domain VHH, also known as a nanobody(Nb). Alpaca is also called Vicugna pacos. Alpaca IgG contains IgG1a, IgG1b, IgG2b, IgG2c and IgG3.

Specificity

Alpaca IgG2c
Isotype: Rabbit IgG

Immunogen

Recombinant Alpaca single variable domain secondary nano antibody

Packaging

100 μg in Glass bottle

Physical form

Lyophilized from 10mM PBS (pH 7.5), 0.05% sucrose, 0.1% trehalose

Reconstitution

Add 100uL dH2O or 100uL dH2O with 50% Glycerol to a final concentration of 1mg/mL

Storage and Stability

After reconstitution, store at –20 °C(Avoid freeze / thaw cycles). Stable for 12 months at -20°C

Other Notes

No cross-reactivity with Alpaca IgG1/2b

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H317,H412
• pcodes: P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313
• Hazard Classifications: Aquatic Chronic 3 - Skin Sens. 1
• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable